Results 231 to 240 of about 286,011 (299)

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins, Julyane N. S. Kaihara, Diego Fortes Salgueiro, Viviane Cunha Cardoso, Silvana Maria Quintana, Ricardo Carvalho Cavalli, Valerio Garrone Barauna, Valeria Cristina Sandrim   +7 more
wiley   +1 more source

Reduced gastrointestinal iron uptake in pulmonary arterial hypertension: a prospective cross-sectional study. [PDF]

Respir Res
Repsold L, Harutyunova S, Grünig E, Benjamin N, Xanthouli P, Egenlauf B, Florea A, Shaukat M, Sparla R, Mertens C, Muckenthaler MU, Eichstaedt CA.   +11 more
europepmc   +1 more source

Validation of the fullPIERS model for predicting severe maternal outcomes in preeclampsia in five Brazilian centers

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The objective of this study is to validate the fullPIERS (Pre‐eclampsia Integrated Estimate of Risk) prognostic model in a large, multicenter cohort of Brazilian women with preeclampsia and to determine the optimal cutoff for clinical application in the Brazilian context.
Pedro do Valle Teichmann, José Paulo Siqueira Guida, Maria Laura Costa, Leila Katz, Melania Maria Amorim, Jussara Mayrink, Giorgio Tondello, Sergio Hofmeister de Almeida Martins Costa, José Geraldo Lopes Ramos   +8 more
wiley   +1 more source

Assessing the feasibility of using smartphone data to identify risk of idiopathic pulmonary arterial hypertension. [PDF]

NPJ Cardiovasc Health
Delgado-SanMartin JA, Keles M, Errington N, Schuetz N, Johnson A, Gupta V, Hershman S, Toshner M, Wilkins MR, Kiely DG, Thompson R, Ashley E, Wang D, Lawrie A.   +13 more
europepmc   +1 more source

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, EarlyView.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

PAH-former: Transfer learning for efficient discovery of pulmonary arterial hypertension-associated genes. [PDF]

PLoS One
Kawakami T, Hosokawa S, Ito M, Kurozumi A, Tanaka R, Minatsuki S, Ishida J, Isagawa T, Kodera S, Takeda N.   +9 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

The Pathophysiology, Mechanism, Diagnosis, and Management of Pulmonary Arterial Hypertension: A Comprehensive Literature Review. [PDF]

US Cardiol
Gangavelli A, Fabiano RC, Riad M, Kaur G, Rai D, Gomberg-Maitland M.   +5 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source