Advanced Science, EarlyView.Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang +25 more
wiley +1 more source
Goal-directed therapy in intraoperative fluid and hemodynamic management. [PDF]
, 2013 Intraoperative fluid management is pivotal to the outcome and success of surgery, especially in high-risk procedures. Empirical formula and invasive static monitoring have been traditionally used to guide intraoperative fluid management and assess volume
Gutierrez, Maria Cristina +2 more
core +1 more source
Advanced Science, EarlyView.A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng +40 more
wiley +1 more source
“Bendy” stents help negotiate hairpin intracardiac curves [PDF]
, 2015 Simple transposition of the great arteries (TGA) occurs in 0.2 per 1000 live births. The condition is surgically repaired in the neonatal period by the arterial switch procedure (ASO) sometimes preceded by an atrial septostomy.
Bugeja, Justine +2 more
core
STUDIES OF CONGENITAL HEART DISEASE. II. THE PRESSURE AND OXYGEN CONTENT OF BLOOD IN THE RIGHT AURICLE, RIGHT VENTRICLE, AND PULMONARY ARTERY IN CONTROL PATIENTS, WITH OBSERVATIONS ON THE OXYGEN SATURATION AND SOURCE OF PULMONARY “CAPILLARY” BLOOD 1 [PDF]
, 1947 L Dexter +5 more
openalex +1 more source
Molecular Creep Induced Fatigue Rupture of Fibrin Clots
Advanced Science, EarlyView.Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu +5 more
wiley +1 more source
Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, EarlyView.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source
Rare Presentation of Left Lower Lobe Pulmonary Artery Dissection
Case Reports in Medicine, 2017 Background. Pulmonary arterial dissection with chronic pulmonary arterial hypertension as its major cause is a very rare but life-threatening condition.
René Hako +7 more
doaj +1 more source
The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]
, 2008 The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek +5 more
core +1 more source
Congenital Aortic Septal Defect with Communication between Aorta and Pulmonary Artery [PDF]
, 1950 Herta Spencer, Harvey J. Dworken
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