Results 191 to 200 of about 2,377,574 (384)

Flash pulmonary edema: A rare cause and possible mechanisms

open access: yesTurkish Journal of Emergency Medicine, 2017
Flash pulmonary edema frequently develop in case of bilateral renal artery stenosis and unilateral renal artery stenosis with functional solitary kidney.
Tolga Cimen   +4 more
doaj  

Establishment of rat model for aspiration pneumonia and potential mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu   +7 more
wiley   +1 more source

Self-adaptive vision-language model for 3D segmentation of pulmonary artery and vein [PDF]

open access: yesarXiv
Accurate segmentation of pulmonary structures iscrucial in clinical diagnosis, disease study, and treatment planning. Significant progress has been made in deep learning-based segmentation techniques, but most require much labeled data for training. Consequently, developing precise segmentation methods that demand fewer labeled datasets is paramount in
arxiv  

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang   +5 more
wiley   +1 more source

Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof‐of‐concept study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt   +7 more
wiley   +1 more source

An optimized perfusate for enhanced rat ex vivo lung perfusion and lung transplant models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We explored a low‐cost and efficient perfusate composition for use in rat ex vivo lung perfusion (EVLP) and lung transplant models. This perfusate demonstrates better biocompatibility, likely due to a reduction in immune responses associated with high doses of xenogenic proteins, resulting in less lung injury posttransplantation.
Jie Zhang, Xuanlin Zhang, Jianxing He
wiley   +1 more source

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei   +4 more
wiley   +1 more source

TabMixer: Noninvasive Estimation of the Mean Pulmonary Artery Pressure via Imaging and Tabular Data Mixing [PDF]

open access: yesarXiv
Right Heart Catheterization is a gold standard procedure for diagnosing Pulmonary Hypertension by measuring mean Pulmonary Artery Pressure (mPAP). It is invasive, costly, time-consuming and carries risks. In this paper, for the first time, we explore the estimation of mPAP from videos of noninvasive Cardiac Magnetic Resonance Imaging.
arxiv  

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