Results 231 to 240 of about 2,377,574 (384)

Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,4‐dioic acid (SSDA) and 4‐OH‐solanidine as diet‐derived cytochrome P450 2D6 (CYP2D6) biomarkers in a ...
Jens Andreas Sarömba   +9 more
wiley   +1 more source

Vascular co‐option and vasculogenic mimicry mediate resistance to antiangiogenic strategies

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The concept that all the tumors need the formation of new vessels to grow inspired the hypothesis that inhibition of angiogenesis would have led to “cure” cancer. The expectancy that this type of therapy would have avoided the insurgence of resistance was based on the concept that targeting normal vessels, instead of the cancer ...
Francesco Pezzella, Domenico Ribatti
wiley   +1 more source

Recurrent pulmonary artery pseudoaneurysm in a patient with tetralogy of Fallot. [PDF]

open access: yesKardiochir Torakochirurgia Pol
Skorek P   +3 more
europepmc   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan   +3 more
wiley   +1 more source

A Rare Case of Dislodged Chemoport Catheter Entrapment in the Pulmonary Artery. [PDF]

open access: yesCase Rep Vasc Med
Shrestha S   +8 more
europepmc   +1 more source

The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction

open access: yesClinical and Experimental Dental Research, Volume 8, Issue 6, Page 1449-1455, December 2022., 2022
Abstract Objectives The extraction of a tooth exacerbates the stress in diabetic patients leading to diabetic complications so the aim was to evaluate the changes in blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction to pay special attention during a routine surgical procedure.
Zana Agani   +6 more
wiley   +1 more source

Pulmonary Artery Intimal Sarcoma. [PDF]

open access: yesJ Belg Soc Radiol
Mercken K, Sneyers V, Di Dedda E.
europepmc   +1 more source

Home - About - Disclaimer - Privacy