Results 31 to 40 of about 2,337,645 (271)

Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia

American Journal of Hematology, Volume 98, Issue 2, Page 338-347, February 2023., 2023
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo, Christian Buske, Judith Trotman, Shayna Sarosiek, Steven P. Treon   +4 more
wiley   +1 more source

Study of Two-stage Injection of Contrast Agent in Combination with Bolus Tracking Technique in Computed Tomography Pulmonary Angiography

CT Lilun yu yingyong yanjiu, 2023
Objective: To investigate the utility of a two-stage injection of contrast agent combined with a bolus tracking technique in computed tomography (CT) pulmonary angiography.
Yunfu LIU, Tianliang KANG, Yongxian ZHANG, Wei LI, Qinggang XU, Xinyan WANG, Junfang XIAN, Yantao NIU   +7 more
doaj   +1 more source

Birth defects associated with paternal firefighting in the National Birth Defects Prevention Study

American Journal of Industrial Medicine, Volume 66, Issue 1, Page 30-40, January 2023., 2023
Abstract Background Few studies have evaluated birth defects among children of firefighters. We investigated associations between birth defects and paternal work as a firefighter compared to work in non‐firefighting and police officer occupations. Methods We analyzed 1997–2011 data from the multi‐site case‐control National Birth Defects Prevention ...
Miriam R. Siegel, Carissa M. Rocheleau, Brittany S. Hollerbach, Amel Omari, Sara A. Jahnke, Lynn M. Almli, Andrew F. Olshan, National Birth Defects Prevention Study   +7 more
wiley   +1 more source

Reconstruction of anomalous left coronary artery from pulmonary artery in an adult patient: a case report

Journal of Cardiothoracic Surgery, 2019
Background Anomalous left coronary artery from the pulmonary artery is a congenital heart disease in which myocardial ischemia occurs within 1 year of birth. Adults have been reported to survive owing to the development of collateral perfusion from right
Kazuki Mori, Hirofumi Anai, Tomoyuki Wada, Takashi Shuto, Shinji Miyamoto   +4 more
doaj   +1 more source

Comprehensive genetic screening for vascular Ehlers–Danlos syndrome through an amplification‐based next‐generation sequencing system

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 37-51, January 2023., 2023
Abstract Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder (HCTD) characterized by arterial dissection/aneurysm/rupture, sigmoid colon rupture, or uterine rupture. Diagnosis is confirmed by detecting heterozygous variants in COL3A1.
Tomomi Yamaguchi, Shujiro Hayashi, Daisuke Hayashi, Takeshi Matsuyama, Norimichi Koitabashi, Kenichi Ogiwara, Masaaki Noda, Chiai Nakada, Shinya Fujiki, Akira Furutachi, Yasuhiko Tanabe, Michiko Yamanaka, Aki Ishikawa, Miyako Mizukami, Asako Mizuguchi, Kazumitsu Sugiura, Makoto Sumi, Hirokuni Yamazawa, Atsushi Izawa, Yuko Wada, Tomomi Fujikawa, Yuri Takiguchi, Keiko Wakui, Kyoko Takano, Shin‐Ya Nishio, Tomoki Kosho   +25 more
wiley   +1 more source

A Probabilistic Neural Twin for Treatment Planning in Peripheral Pulmonary Artery Stenosis [PDF]

arXiv, 2023
The substantial computational cost of high-fidelity models in numerical hemodynamics has, so far, relegated their use mainly to offline treatment planning. New breakthroughs in data-driven architectures and optimization techniques for fast surrogate modeling provide an exciting opportunity to overcome these limitations, enabling the use of such ...
arxiv  

A rare homozygous missense GDF2 (BMP9) mutation causing PAH in siblings: Does BMP10 status contribute?

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 228-233, January 2023., 2023
Abstract Pulmonary arterial hypertension (PAH) is a disease characterized by pathological remodeling of the pulmonary vasculature causing elevated pulmonary artery pressures and ultimately, right ventricular failure from chronic pressure overload. Heterozygous pathogenic GDF2 (encoding bone morphogenetic protein 9 (BMP9)) variants account for some (>1%)
Paul Upton, Susan Richards, Angela Bates, Karen Y. Niederhoffer, Nicholas W. Morrell, Susan Christian   +5 more
wiley   +1 more source

Transcatheter embolization of a Rasmussen aneurysm via pulmonary artery with n-butyl cyanoacrylate and iodized oil mixture injection with balloon occlusion

Journal of Vascular Surgery Cases and Innovative Techniques, 2016
We describe a new approach to effective embolization of Rasmussen aneurysm by simultaneous devascularization of the pseudoaneurysm and systemic artery-to-pulmonary artery anastomoses.
Yukichi Tanahashi, MD, Hiroshi Kondo, MD, Marie Osawa, MD, Takahiro Yamamoto, MD, Masao Yamaguchi, MD, Shigeru Furui, MD   +5 more
doaj   +1 more source

Pulmonary Artery Denervation Reduces Pulmonary Artery Pressure and Induces Histological Changes in an Acute Porcine Model of Pulmonary Hypertension

Circulation. Cardiovascular Interventions, 2015
Background—Pulmonary arterial hypertension is a devastating disease with high morbidity and mortality and limited treatment options. Recent studies have shown that pulmonary artery denervation improves pulmonary hemodynamics in an experimental model and ...
A. Rothman, N. Arnold, W. Chang, O. Watson, A. Swift, R. Condliffe, C. Elliot, D. Kiely, S. Suvarna, J. Gunn, A. Lawrie   +10 more
semanticscholar   +1 more source

Topology Repairing of Disconnected Pulmonary Airways and Vessels: Baselines and a Dataset [PDF]

arXiv, 2023
Accurate segmentation of pulmonary airways and vessels is crucial for the diagnosis and treatment of pulmonary diseases. However, current deep learning approaches suffer from disconnectivity issues that hinder their clinical usefulness. To address this challenge, we propose a post-processing approach that leverages a data-driven method to repair the ...
arxiv