Results 81 to 90 of about 2,337,645 (271)

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Pulmonary arterial hypertension: pathogenesis and clinical management

British medical journal, 2018
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of pulmonary hypertension that primarily affects the pulmonary vasculature.
T. Thenappan, M. Ormiston, J. Ryan, S. Archer   +3 more
semanticscholar   +1 more source

Attention based CNN-LSTM Network for Pulmonary Embolism Prediction on Chest Computed Tomography Pulmonary Angiograms [PDF]

arXiv, 2021
With more than 60,000 deaths annually in the United States, Pulmonary Embolism (PE) is among the most fatal cardiovascular diseases. It is caused by an artery blockage in the lung; confirming its presence is time-consuming and is prone to over-diagnosis.
arxiv  

The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ

Advanced Science, EarlyView.
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo, Biao Huang, Ping Xu, Hao Wang, Baozhen Zhang, Li Lin, Jiujiang Liao, Mingyu Hu, Xiyao Liu, Jiayu Huang, Yong Fu, Mark D. Kilby, Rodney E. Kellems, Xiujun Fan, Yang Xia, Philip N. Baker, Hongbo Qi, Chao Tong   +17 more
wiley   +1 more source

A computed tomography‐based survey of paramedullary diverticula in extant Aves

The Anatomical Record, Volume 306, Issue 1, Page 29-50, January 2023., 2023
Abstract Avian respiratory systems are comprised of rigid lungs connected to a hierarchically organized network of large, regional air sacs, and small diverticula that branch from them. Paramedullary diverticula are those that rest in contact with the spinal cord, and frequently invade the vertebral canal.
Jessie Atterholt, Mathew J. Wedel
wiley   +1 more source

A rare case of pulmonary atresia with ventricular septal defect with right-sided aortic arch

Radiology Case Reports, 2023
Pulmonary atresia with ventricular septal defect is a congenital heart malformation in which a lack of continuity between ventricles and the pulmonary artery is accompanied by ventricular septal defect.
Dian Komala Dewi, MD, Muhammad Danil, MD
doaj  

When a pulmonary embolism is not a pulmonary embolism: a rare case of primary pulmonary leiomyosarcoma [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2015
Arterial leiomyosarcomas account for up to 21% of vascular leiomyosarcomas, with 56% of arterial leiomyosarcomas occurring in the pulmonary artery. While isolated cases of primary pulmonary artery leiomyosarcoma document survival up to 36 months after ...
Nargiz Muganlinskaya, Amanda Guzman, Chanukya Dahagam, Stephen R. Selinger   +3 more
doaj   +1 more source

Reference Values for Normal Pulmonary Artery Dimensions by Noncontrast Cardiac Computed Tomography: The Framingham Heart Study

Circulation Cardiovascular Imaging, 2012
Background— Main pulmonary artery diameter (mPA) and ratio of mPA to ascending aorta diameter (ratio PA) derived from chest CT are commonly reported in clinical practice.
Q. Truong, J. Massaro, Ian S. Rogers, A. Mahabadi, Matthias F Kriegel, C. Fox, C. O’Donnell, U. Hoffmann   +7 more
semanticscholar   +1 more source

MEDPSeg: Hierarchical polymorphic multitask learning for the segmentation of ground-glass opacities, consolidation, and pulmonary structures on computed tomography [PDF]

arXiv, 2023
The COVID-19 pandemic response highlighted the potential of deep learning methods in facilitating the diagnosis, prognosis and understanding of lung diseases through automated segmentation of pulmonary structures and lesions in chest computed tomography (CT).
arxiv  

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source