Results 111 to 120 of about 1,137,821 (328)

From Trials to Practice: A 2025 Review of Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Efficacy Across Clinical Studies and Real‐World Evidence

European Journal of Haematology, EarlyView.
ABSTRACT B‐cell maturation antigen (BCMA)‐directed chimeric antigen receptor (CAR) T‐cell therapies have revolutionized the approach and management of relapsed/refractory multiple myeloma (RRMM), and as of 2025, idecabtagene vicleucel (ide‐cel) and ciltacabtagene autoleucel (cilta‐cel) are the only BCMA‐targeted CAR T‐cell therapies approved by the FDA.
Hector Garcia Pleitez, Sakditad Saowapa, Andrea Ortiz Maldonado, Chanakarn Kanitthamniyom, Diego Olavarria Bernal, Lukman Tijani   +5 more
wiley   +1 more source

Pulmonary Aspergillosis: An Evolving Challenge for Diagnosis and Treatment

Infectious Diseases and Therapy, 2020
Aspergillus is a mold that may lead to different clinical pictures, from allergic to invasive disease, depending on the patient’s immune status and structural lung diseases.
Alessandro Russo, Giusy Tiseo, Marco Falcone, Francesco Menichetti   +3 more
doaj   +1 more source

Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis [PDF]

, 2020
Histoplasma capsulatum infection is a rare complication in the allogeneic stem cell transplant patients. Minimal guidance exists on how to appropriately manage histoplasmosis in these patients.
Agrawal, Vaibhav, Brinda, Bryan J., Farag, Sherif S.   +2 more
core   +1 more source

COVID-19 Associated Invasive Pulmonary Aspergillosis: Diagnostic and Therapeutic Challenges

Journal of Fungi, 2020
Aspergillus co-infection in patients with severe coronavirus disease 2019 (COVID-19) pneumonia, leading to acute respiratory distress syndrome, has recently been reported.
Aia Mohamed, T. Rogers, A. F. Talento
semanticscholar   +1 more source

HIV: is it now a thing of the past?

Internal Medicine Journal, EarlyView.
Abstract Effective antiviral therapy for human immunodeficiency virus (HIV) has substantially reduced HIV‐associated morbidity and mortality for people living with HIV (PLWH). The use of antiviral therapies as prevention, most notably pre‐exposure prophylaxis (PrEP) as well as treatment as prevention (TasP), has significantly reduced the number of new ...
Jeffrey John Post
wiley   +1 more source

Reciprocal Inhibition of Adiponectin and Innate Lung Immune Responses to Chitin and Aspergillus fumigatus [PDF]

, 2019
Chitin is a structural biopolymer found in numerous organisms, including pathogenic fungi, and recognized as an immune-stimulating pathogen associated molecular pattern by pattern recognition molecules of the host immune system.
Amarsaikhan, Nansalmaa, Gravely, Haley, Sands, Ethan M., Stolz, Dylan J., Templeton, Steven P., Tsoggerel, Angar, Wilcox, Amber   +6 more
core   +4 more sources

Aspergillus nodules; another presentation of Chronic Pulmonary Aspergillosis [PDF]

, 2016
BACKGROUND: There are a number of different manifestations of pulmonary aspergillosis. This study aims to review the radiology, presentation, and histological features of lung nodules caused by Aspergillus spp.
Anna Sharman, David W. Denning, Eavan G. Muldoon, Iain Page, Paul Bishop   +4 more
core   +1 more source

Pulmonary aspergillosis in critically ill patients with Coronavirus Disease 2019 (COVID-19)

Medical Mycology, 2020
Occurrence of putative invasive pulmonary aspergillosis was screened in 153 consecutive adult intensive care unit (ICU) patients with respiratory samples addressed for mycological diagnosis during a 6-week period at the emergence of coronavirus disease ...
D. Dupont, J. Menotti, J. Turc, C. Miossec, F. Wallet, J. Richard, L. Argaud, S. Paulus, M. Wallon, F. Ader, F. Persat   +10 more
semanticscholar   +1 more source

The Changing Epidemiology of Breakthrough Invasive Fungal Disease in Allogeneic Hematopoietic Stem Cell Transplant Recipients in the Era of Modified‐Release Posaconazole Prophylaxis

Transplant Infectious Disease, EarlyView.
This single‐center retrospective cohort study on 300 allogeneic hematopoietic stem cell transplant recipients from January 2017 to May 2020, in which posaconazole modified release was the most common primary antifungal prophylaxis, demonstrated a breakthrough invasive fungal disease (bIFD) rate of 9%, with associated significant all‐cause mortality at ...
Shio Yen Tio, Chin Fen Neoh, David Ritchie, Lynette Chee, David C. M. Kong, Leon J. Worth, Michelle K. Yong, Monica A. Slavin   +7 more
wiley   +1 more source

Prospective evaluation of a new Aspergillus IgG EIA kit for the diagnosis of chronic and allergic pulmonary aspergillosis [PDF]

, 2016
International ...
Bailly, S., Brenier-Pinchart, M. P., Camara, B., Cornet, M., Dumollard, C., Gangneux, Jean-Pierre, Grenouillet, F., Pelloux, H., Perriot, S., Persat, F., Pinel, C., Saint-Raymond, C., Valot, S.   +12 more
core   +4 more sources