Results 281 to 290 of about 1,137,821 (328)

CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models

Science Translational Medicine, 2022
Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive and innate immune cells that respond to A.
Michelle Seif, T. K. Kakoschke, F. Ebel, M. Bellet, Nora Trinks, G. Renga, M. Pariano, L. Romani, Beeke Tappe, D. Espie, E. Donnadieu, Kerstin Hünniger, A. Häder, Markus Sauer, D. Damotte, M. Alifano, P. L. White, M. Backx, T. Nerreter, M. Machwirth, O. Kurzai, Sabrina Prommersberger, H. Einsele, M. Hudecek, J. Löffler   +24 more
semanticscholar   +1 more source

Invasive pulmonary aspergillosis

Revista Clínica Española (English Edition), 2020
AbstractInvasive pulmonary aspergillosis (IPA) remains difficult to diagnose and to treat. Most common risk factors are prolonged neutropenia, hematopoietic stem cell or solid organ transplantation, inherited or acquired immunodeficiency, administration of steroids or other immunosuppressive agents including monoclonal antibodies and new small ...
L.A. Fernández-Bermejo, G. Ramírez-Olivencia   +1 more
openaire   +6 more sources

Invasive Pulmonary Aspergillosis

Respiration, 2002
<i>Background:</i> Invasive pulmonary aspergillosis usually occurs in immunocompromised patients. Mild abnormality of host defence is usually present in the chronic necrotising form of the disease. Acute aspergillus pneumonia usually affects patients who are seriously immunocompromised.
Ema Mušič, Izidor Kern, Sabina Škrgat Kristan   +2 more
openaire   +5 more sources

Pulmonary aspergillosis

The Netherlands Journal of Medicine, 2001
Aspergillus species are ubiquitous in the environment and are inevitably inhaled into the airways. Inhalation of Aspergillus conidia or mycelium fragments may result in colonisation of the airways. In susceptible hosts colonisation may subsequently cause disease.
J F, Tomee, T S, van der Werf
openaire   +2 more sources

Invasive pulmonary aspergillosis

Expert Review of Anti-infective Therapy, 2005
In susceptible patients, invasive aspergillosis has a high incidence and a mortality of up to 80%. The diagnosis of this condition is difficult, especially in the early stages of the disease and, as a consequence, antifungal therapy, despite its expense and toxicity, is often initiated empirically.
Sarah R. Doffman, Samir G. Agrawal, Jeremy S. Brown   +2 more
openaire   +5 more sources

High rates of influenza-associated invasive pulmonary aspergillosis may not be universal: a retrospective cohort study from Alberta, Canada.

Clinical Infectious Diseases, 2020
Invasive pulmonary aspergillosis (IPA) complicated 7.2% of patients with influenza-associated respiratory failure in Edmonton, Alberta, from 2014-2019, ranging from 0-23.1% in different influenza seasons.
Ilan S. Schwartz, Daniel Z. P. Friedman, Lori Zapernick, T. Dingle, N. Lee, W. Sligl, N. Zelyas, Stephanie W. Smith   +7 more
semanticscholar   +1 more source

Pathophysiology of pulmonary aspergillosis

Journal of Infection and Chemotherapy, 2004
A description of the pathophysiology of aspergillosis is followed by a review of investigational considerations of animal models. Because a large body of invasive Aspergillus infection occurs as opportunistic infection, there is a large spectrum of the histopathological feature of lesions demonstrated at the site of infection.
Chikako Hasegawa, Hiroko Nonaka, Kazutoshi Shibuya, Tsutomu Hatori, Tsunehiro Ando, Tadashi Nagayama, Megumi Wakayama, Shigeharu Hamatani   +7 more
openaire   +2 more sources

Pulmonary aspergillosis in Argyll

British Journal of Diseases of the Chest, 1965
Summary All the chest radiographs taken in Argyll from 1954 to 1963 have been investigated and the fifty-six patients found to have residual tuberculous or other cavitation, with or without any suggestion of aspergilloma, have been examined further. Six of these (approximately one in ten) were discovered to have pulmonary aspergillomas.
openaire   +3 more sources

Pulmonary Aspergillosis in Greece

Diseases of the Chest, 1952
Summary 1) Pulmonary aspergillosis is a rare disease difficult to diagnose because it is often confused with pulmonary tuberculosis. 2) In all cases of pulmonary affections where pulmonary tuberculosis is excluded, search for pulmonary aspergillosis should not be omitted.
openaire   +3 more sources

Invasive Pulmonary Aspergillosis

JAMA: The Journal of the American Medical Association, 1980
To the Editor:— In reference to the article "Invasive Pulmonary Aspergillosis Associated With Influenza" by Fischer and Walker (241:1493, 1979), mention is made that invasive pulmonary aspergillosis is usually seen in the compromised host and that invasive disease is rare in normal persons. The authors mention only 13 cases of pulmonary aspergillosis
openaire   +3 more sources