Results 71 to 80 of about 10,740,382 (298)

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

Pulmonary regional blood flow: validation of low-dose two-volume dynamic CT perfusion imaging in a swine model

European Radiology Experimental
Background We aimed to validate a low-dose two-volume pulmonary computed tomography (CT) perfusion technique. Methods Five Yorkshire swine (weight 53.6 ± 2.6 kg) underwent 21 independent CT perfusion acquisitions. Intravenous contrast material (370 mg/mL
Yixiao Zhao, Nile Luu, Logan Hubbard, Shant Malkasian, Sabee Molloi   +4 more
doaj   +1 more source

Pulmonary vascular pruning in smokers with bronchiectasis

ERJ Open Research, 2018
There are few studies looking at the pulmonary circulation in subjects with bronchiectasis. We aimed to evaluate the intraparenchymal pulmonary vascular structure, using noncontrast chest computed tomography (CT), and its clinical implications in smokers
Alejandro A. Diaz, Diego J. Maselli, Farbod Rahaghi, Carolyn E. Come, Andrew Yen, Erick S. Maclean, Yuka Okajima, Carlos H. Martinez, Tsuneo Yamashiro, David A. Lynch, Wei Wang, Gregory L. Kinney, George R. Washko, Raúl San José Estépar   +13 more
doaj   +1 more source

Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog [PDF]

, 2008
A five-month-old female Jack Russell terrier was presented for investigation of acute lethargy, anorexia, coughing, respiratory distress and weakness. Examination findings included cyanosis, a grade 3 of 6 systolic heart murmur and prolonged capillary ...
Russell, N.J., Nicholls, P.K., Olivry, T., Irwin, P.J., Hopper, B.J.   +4 more
core  

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Evaluation of pulmonary functions in pediatric patients with beta-thalassemia major

Al-Azhar Assiut Medical Journal, 2019
Background Thalassemia is a challenging health problem all over the world, especially in Mediterranean areas. Its effect on pulmonary function has not been well studied.
Lotfy Abdelfattah Elsehaimy, Mokhles Abdel Fadil Zineldin, Wafaa Alsaed Khalil   +2 more
doaj   +1 more source

High tidal volume ventilation is not deleterious in infant rats exposed to severe hemorrhage [PDF]

, 2010
BACKGROUND: Both high tidal volume (VT) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung injury in infant rats exposed to severe hemorrhage.
Nicholls, Philip K., Sly, P.D., Hantos, Z, Sly, Peter D., Berry, L.J., Cannizzaro, V; https://orcid.org/, Hantos, Zoltán, Cannizzaro, V., Berry, Luke J., Nicholls, P.K., Hantos, Z., Nicholls, P K, Sly, P D, Berry, L J, Cannizzaro, Vincenzo   +14 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Effects of serotonin on pulmonary blood volume in the dog

, 1962
Changes in pulmonary blood volume produced by continuous intravenous infusion of serotonin (5-hydroxytryptamine) were measured in 16 experiments on ten dogs.
Charles J. McGaff, William R. Milnor
core   +1 more source