Results 171 to 180 of about 1,949,289 (385)

Effects of 12 and 17 cmH2O positive end-expiratory pressure applied after alveolar recruitment maneuver on pulmonary gas exchange and compliance in isoflurane-anesthetized horses

, 2018
Felipe SRM. Andrade, Lara Lopes Facó, Keila Kazue Ida, Luis CLC Silva, Denise Tabacchi Fantoni, Aline Magalhães Ambrósio   +5 more
openalex   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

The relationship of pulmonary vascular resistance and compliance to pulmonary artery wedge pressure during submaximal exercise in healthy older adults

Journal of Physiology, 2016
S. Wright, J. Granton, S. Esfandiari, J. Goodman, S. Mak   +4 more
semanticscholar   +1 more source

Value of Echo-Doppler Derived Pulmonary Vascular Resistance, Net-Atrioventricular Compliance and Tricuspid Annular Velocity in Determining Exercise Capacity in Patients With Mitral Stenosis

, 2007
Eui‐Young Choi, Jaemin Shim, Sung‐Ai Kim, Chi Young Shim, Se‐Jung Yoon, Seok‐Min Kang, Donghoon Choi, Jong‐Won Ha, Se‐Joong Rim, Yangsoo Jang, Namsik Chung   +10 more
openalex   +2 more sources

Costs of chronic obstructive pulmonary disease in relation to compliance with guidelines: a study in the primary care setting [PDF]

, 2013
Marc Miravitlles, Antoni Sicras, Carlos Crespo, Maribel Cuesta, Max Brosa, J Galera, Raquel Lahoz, Marta Lleonart, Maria Isabel Riera   +8 more
openalex   +1 more source

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

Advanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu, Yan Gao, Yadong Guo, Junfeng Zhang, Wentao Zhang, Zhuoran Gu, Haotian Chen, Chengqi Jin, Peng Luo, Shiyu Mao, Yajuan Hao, Shuo Shi, Xudong Yao   +12 more
wiley   +1 more source

Comparison of Continuous Milrinone Versus Dobutamine on Pulmonary Pressures in Patients With Advanced Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Misha Dagan, Swetha Vasudevan, Malanka Lankaputhra, Timothy Yeung, Victoria Warner, Kellie Easton, Ashlee Considine, Rebecca Downes, Donna Vizi, Angeline Leet, James L. Hare, Andrew Taylor, Peter Bergin, Hitesh C. Patel, David M. Kaye   +14 more
doaj   +1 more source

Illuminating the Importance of Pulmonary Arterial Compliance in Pulmonary Hypertension

American Journal of Respiratory and Critical Care Medicine, 2023
Jason Weatherald, Umberto Zanini, Marc Humbert   +2 more
openaire   +2 more sources

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser induced graphene offers a scalable route to flexible, porous gas sensor with tunable properties and self heating functionality. This summarizes the overview of the design and application landscape of LIG‐based wearable gas sensor in healthcare. ABSTRACT Direct laser irradiation of carbonaceous precursors such as polyimide and wood is a scalable ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source