What role does the right side of the heart play in circulation? [PDF]
Right ventricular failure (RVF) is an underestimated problem in intensive care. This review explores the physiology and pathophysiology of right ventricular function and the pulmonary circulation.
Cecconi, M, Johnston, E, Rhodes, A
core +2 more sources
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression [PDF]
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases ...
A Babusyte +63 more
core +6 more sources
Effect of left atrial compliance on pulmonary artery pressure: a case report
Background Left ventricular diastolic dysfunction, with secondary atrial pressure elevation, is a well-known concept. On the contrary, effect of left atrial compliance on pulmonary pressure is rarely considered.
Jani Dinesh +3 more
doaj +1 more source
Magnetic resonance imaging of pulmonary arterial compliance after pulmonary endarterectomy [PDF]
In CTEPH patients who have undergone pulmonary endarterectomy, exercise capacity is better associated with changes in invasively measured pulmonary arterial compliance than with changes in magnetic resonance imaging of pulmonary artery stiffnesshttp://bit.ly ...
Stefano Ghio +11 more
openaire +3 more sources
Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat +31 more
core +1 more source
Background Right heart catheterization (RHC) is a high‐risk procedure in children with pulmonary arterial hypertension without clear guidelines for the indications and targets of invasive reassessment.
Julien Grynblat +13 more
doaj +1 more source
Pulmonary arterial compliance and exercise capacity after pulmonary endarterectomy [PDF]
Patients with chronic thromboembolic pulmonary hypertension (CTEPH), despite successful pulmonary endarterectomy (PEA), can continue to suffer from a limitation in exercise capacity. The objective of this study was to assess whether pulmonary arterial compliance is a predictor of exercise capacity after PEA.Right heart haemodynamics, treadmill ...
Stefano, Ghio +9 more
openaire +3 more sources
Management of Mechanical Ventilation in Decompensated Heart Failure. [PDF]
Mechanical ventilation (MV) is a life-saving intervention for respiratory failure, including decompensated congestive heart failure. MV can reduce ventricular preload and afterload, decrease extra-vascular lung water, and decrease the work of breathing ...
Adams, Jason Y +4 more
core +4 more sources
PurposeThe prone position is commonly used in spinal surgery, but it can lead to decreased lung compliance and increased airway pressure. This study aimed to evaluate the effect of individualized end-inspiratory pause guided by driving pressure on ...
Ting Zhang +5 more
doaj +1 more source
Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]
Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter +15 more
core +2 more sources

