Results 91 to 100 of about 30,235 (338)

The effect of aging and cardiorespiratory fitness on the lung diffusing capacity response to exercise in healthy humans [PDF]

, 2017
Aging is associated with deterioration in the structure and function of the pulmonary circulation. We characterized the lung diffusing capacity for carbon monoxide (DLCO), alveolar-capillary membrane conductance (Dm(CO)), and pulmonary-capillary blood ...
Alex R. Carlson, Andrew D. Miller, Bruce D. Johnson, Bryan J. Taylor, Crapo RO, Georges R, Kirsten E. Coffman, Sackner MA   +7 more
core   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Lung fibrosis and exposure to wood dusts: Two cases report and review of the literature

Medycyna Pracy, 2015
Introduction: Increasing evidence suggests that idiopathic pulmonary fibrosis (IPF) occurs more often in subjects previously exposed to wood dusts than in non-exposed subjects.
Matteo Riccò
doaj   +1 more source

FVC/DLCO identifies pulmonary hypertension and predicts 5-year all-cause mortality in patients with COPD

European Journal of Medical Research, 2023
Background Pulmonary hypertension (PH) is a common complication of chronic obstructive pulmonary disease (COPD). However, it is unknown whether the ratio of forced vital capacity (FVC) to diffusing lung capacity for carbon monoxide (DLCO) can identify PH
Yuer Li, Rui Zhang, Hu Shan, Wenhua Shi, Xiaoli Feng, Haijuan Chen, Xia Yang, Yali Li, Jie Zhang, Ming Zhang   +9 more
doaj   +1 more source

Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. [PDF]

, 2018
IntroductionExposure to secondhand smoke (SHS) is associated with occult obstructive lung disease as evident by abnormal airflow indices representing small airway disease despite having preserved spirometry (normal forced expiratory volume in 1 s-to ...
Arjomandi, Mehrdad, Blanc, Paul D, Bos, Bruce, Elicker, Brett, Geerts, Jeroen, Gold, Warren M, Keene, Jason, Stiner, Rachel K, van Koeverden, Ian, Zeng, Siyang   +9 more
core   +2 more sources

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Physiology of the lung in idiopathic pulmonary fibrosis

European Respiratory Review, 2018
The clinical expression of idiopathic pulmonary fibrosis (IPF) is directly related to multiple alterations in lung function. These alterations derive from a complex disease process affecting all compartments of the lower respiratory system, from the ...
Laurent Plantier, Aurélie Cazes, Anh-Tuan Dinh-Xuan, Catherine Bancal, Sylvain Marchand-Adam, Bruno Crestani   +5 more
doaj   +1 more source

The single-breath diffusing capacity of CO and NO in healthy children of European descent. [PDF]

PLoS ONE, 2014
The diffusing capacity (DL) of the lung can be divided into two components: the diffusing capacity of the alveolar membrane (Dm) and the pulmonary capillary volume (Vc).
Astrid Thomas, Birgitte Hanel, Jacob L Marott, Frederik Buchvald, Jann Mortensen, Kim G Nielsen   +5 more
doaj   +1 more source

Increased levels of hyaluronic acid in bronchoalveolar lavage from patients with interstitial lung diseases, relationship with lung function and inflammatory cells recruitment [PDF]

, 2014
Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It described the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contributes to the recruitment of inflammatory cells associated with ILD.
Auteri, Santiago, Ernst, Glenda, Galíndez, Fernando, Grynblat, Pedro, Hajos, Silvia Elvira, Jancic, Carolina Cristina, Rodriguez Moncalvo, Juan   +6 more
core   +1 more source

Metal–Organic Framework‐Based Antimicrobial Touch Surfaces to Prevent Cross‐Contamination

Advanced Materials, EarlyView.
A MOF‐based antimicrobial door handle cover is developed. It completely inhibits the cross‐contamination of Gram‐positive bacterial species (Staphylococcus aureus, and Enterococcus faecalis), Gram‐negative bacterial species (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii), and fungi (Candida albicans). Abstract Infection diseases
Javier Fonseca, Mary Cano‐Sarabia, Pilar Cortés, Jordi Saldo, David Montpeyó, Julia Lorenzo, Montserrat Llagostera, Inhar Imaz, Daniel Maspoch   +8 more
wiley   +1 more source