Results 301 to 310 of about 234,444 (394)

Surface‐Anchored Ticagrelor Gelatin Nanoparticles‐Platelets System for Enhanced Anti‐PD‐L1 Therapy Response and Boosted Chemotherapeutic Efficacy of Nanomedicines

open access: yesExploration, EarlyView.
Ticagrelor nanoparticles modified platelets could adhere to tumor‐associated platelets by specific recruiting ability and responsively release ticagrelor under MMPs stimulation. The released ticagrelor could inhibit platelets activity, enhancing tumor treatment efficacy.
Qi Lu   +12 more
wiley   +1 more source

A case of pulmonary and cutaneous sarcoidosis. [PDF]

open access: yesBreathe (Sheff)
Foley E   +5 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Comparing multi-texture fibrosis analysis versus binary opacity-based abnormality detection for quantitative assessment of idiopathic pulmonary fibrosis. [PDF]

open access: yesSci Rep
Nowak S   +9 more
europepmc   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

A 23-Plex Cytokine/Chemokine Analysis Identifies TNFRII, MMP-8, and sIL-1RII as Potential Biomarkers for Systemic Sclerosis. [PDF]

open access: yesBiomedicines
Perricone C   +11 more
europepmc   +1 more source

Anthocyanin Extracts From 11 Superfruits Mitigate Oxidative Stress and Inflammatory Damage in HK‐2 Cells Induced by Cadmium Exposure

open access: yesFood Frontiers, EarlyView.
ABSTRACT Cadmium (Cd) pollution has emerged as an escalating threat to human health, with its induced kidney toxicity being closely linked to oxidative stress and inflammation. In this study, we extracted and analyzed primary anthocyanins from 11 superfruits using UPLC‐Triple‐TOF/MS and evaluated their antioxidant capacity through DPPH, ABTS, FRAP, and
Jiaojiao Liang   +7 more
wiley   +1 more source

A risk score to predict postoperative complications in patients with resectable non-small cell lung cancer. [PDF]

open access: yesJ Thorac Dis
Mallaev M   +8 more
europepmc   +1 more source

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