Results 111 to 120 of about 6,515,723 (291)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Impaired Postural Control Reduces Sit-to-Stand-to-Sit Performance in Individuals with Chronic Obstructive Pulmonary Disease [PDF]

, 2014
Background: Functional activities, such as the sit-to-stand-to-sit (STSTS) task, are often impaired in individuals with chronic obstructive pulmonary disease (COPD).
Janssens, L, Burtin, C., Alison K McConnell, Goossens, N., Janssens Lotte, Marc Decramer, McConnell Alison K., Lotte Janssens, Burtin, Chris, Claeys Kurt, Janssens, W, Simon Brumagne, Janssens, Wim, McConnell, AK, Janssens, L., Wim Janssens, Troosters, T, Brumagne, S., McConnell, Alison K., Brumagne Simon, Decramer, Marc, Burtin, C, Pijnenburg, M., Troosters Thierry, Pijnenburg Madelon, Goossens, Nina, Nina Goossens, Chris Burtin, Decramer, M., Goossens, N, Kurt Claeys, Brumagne, S, Pijnenburg, M, Claeys, K., Troosters, T., Decramer Marc, Brumagne, Simon, Madelon Pijnenburg, Claeys, Kurt, Pijnenburg, Madelon, Decramer, M, Goossens Nina, Janssens Wim, Claeys, K, Thierry Troosters, Janssens, W., Troosters, Thierry, Janssens, Lotte, Burtin Chris   +48 more
core   +2 more sources

CAT-test significance in life quality assessment in patients with chronic obstructive pulmonary disease [PDF]

Саратовский научно-медицинский журнал, 2010
Comprehensive analysis of the impact of complex vaccination against pneumococcus, Haemophilus influenzae type b and influenza on performance CAT-test 6 months after vaccination in patients with chronic obstructive pulmonary disease compared with ...
Protasov A.D., Zhestkov A.M, Shanina I.Yu.   +2 more
doaj  

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Unraveling the Complexities of Coagulation Dysfunction in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Investigating the Interplay between Infection, Hypercapnia and Hemostatic Abnormalities

Life and Science
Objective: To understand how the acute exacerbations of chronic obstructive pulmonary disease (COPD) can lead to coagulation dysfunctions causing hemostatic abnormalities (prolonged prothrombin time, slightly longer activated partial thromboplastin time,
Bilal Ahmed, Muhammad Imran, Nimra Naeem, Usman Haider, Muhammad Atif Rauf, Qaiser Iqbal   +5 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Long-acting beta(2)-agonist in addition to tiotropium versus either tiotropium or long-acting beta(2)-agonist alone for chronic obstructive pulmonary disease [PDF]

, 2012
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropium are commonly used for managing persistent symptoms of chronic obstructive pulmonary disease.
Christopher J Cates, Karner, C, Cates, CJ, Charlotta Karner   +3 more
core   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. [PDF]

, 2011
BACKGROUND: The long-term efficacy and safety of aclidinium bromide, a novel, long-acting muscarinic antagonist, were investigated in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
Fabbri, Leonardo M., Caracta, C, Stephen I Rennard, James F Donohue, Caracta, Cynthia, Gil, Esther Garcia, Jones, PW, Donohue, JF, Magnussen, Helgo, Bateman, ED, Nicholas J Gross, Bateman, Eric D, Channez, Pascal, Fabbri, L, Agusti, Alvar, Lamarca R, Gross Nicholas J, Magnussen Helgo, Gil, Esther G, Cynthia Caracta, Caracta Cynthia, Chanez P, Jones, Paul, Agusti Alvar, Paul W Jones, Lamarca, R, Bateman, Eric D., Jones, Paul W., Gross, Nicholas J, Esther Garcia Gil, Agusti A, Gil, Esther, Rosa Lamarca, Alvar Agusti, Jones, Paul W, Chanez, P, Fabbri Leonardo, Magnussen H, Helgo Magnussen, Donohue JF, Gil, EG, Magnussen, H, Donohue James F, Gross, Nicholas J., Garcia Gil, Esther, Jones PW, Rennard, SI, Lamarca, Rosa, Gross NJ, Agusti, A, Caracta C, Eric D Bateman, Jones Paul W, Gil Esther, Chanez, Pascal, Donohue, James F, Donohue, James F., Bateman Eric D, Rennard, Stephen I., Bateman, Eric, Rennard Stephen I, Gross, Nicholas, Gross, NJ, Pascal Chanez, Rennard, Stephen, Bateman ED, Agustí García-Navarro, Àlvar, Lamarca Rosa, Chanez Pascal, Rennard, Stephen I, Rennard SI, Gil EG, Fabbri, Leonardo, Leonardo Fabbri, Donohue, James   +74 more
core   +2 more sources