Results 141 to 150 of about 387,443 (303)

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Geographic distribution of asthma and chronic obstructive pulmonary disease hospitalisations in Australia: 2007-08 to 2009-10 [PDF]

, 2013
This report shows how asthma and chronic obstructive pulmonary disease (COPD) hospitalisations vary across Australia. It also examines the association between these hospitalisation rates and socioeconomic status (SES), remoteness and the proportion of

core  

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD)

, 2006
Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far.
David A Groneberg, Wagner, Ulrich, Fischer, Axel, Groneberg, Jan David Alexander, Groneberg David A, Welte, Tobias, Fehmann Hans-Christoph, Staats Petra, Axel Fischer, Welte Tobias, Fischer Axel, Ulrich Wagner, Tobias Welte, Fehmann, Hans-Christoph, Petra Staats, Staats, Petra, Hans-Christoph Fehmann, Wagner Ulrich   +17 more
core   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

A pilot study of the impact of high-frequency chest wall oscillation in chronic obstructive pulmonary disease patients with mucus hypersecretion

, 2011
Indranil Chakravorty1, Kamaljit Chahal2, Gillian Austin21St George's Hospital, London, 2East and North Hertfordshire NHS Trust, Lister Hospital and Primary Care Trust, Stevenage, Hertfordshire, UKIntroduction: Chronic obstructive pulmonary ...
Chahal, K, Chakravorty, I, Chahal K, null Chahal, Austin G, Chakravorty I, Indranil Chakravorty, Austin, G, null Austin   +8 more
core   +1 more source

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source

Association of single-nucleotide polymorphism with spirometry indices and pulmonary ventilation characteristics in patients with chronic obstructive pulmonary disease

Journal of International Medical Research
Objectives Genome-wide association studies have identified FAM13A as a gene linked to chronic obstructive pulmonary disease. Several single-nucleotide polymorphisms—notably, rs7671167, rs2869967, rs2869966, and rs17014601—are associated with chronic ...
Binh Huy Nguyen, Nhung Thi Cam Tran, Chuong Quoc Ho, Tam Thai Thanh Tran, Hong Ngoc Phan, De Van Tran, Nga Thi Ngoc Pham, Kien Trung Nguyen, Khanh Hoang Pham   +8 more
doaj   +1 more source

Respiratory medication use in Australia 2003–2013: treatment of asthma and COPD [PDF]

, 2015
This report describes patterns of dispensing of respiratory medications in Australia through detailed analyses of Pharmaceutical Benefits Scheme data, as well as other sources, to draw inferences about respiratory medication use among patients with ...
Leanne Poulos, Patricia Correll, H. K. Reddel, Rosario Ampon, Guy Marks   +4 more
core  

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease.

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Seniukovich, A, Alieksei Seniukovich, Kew, KM, Kayleigh M Kew   +3 more
core   +1 more source