Results 51 to 60 of about 387,443 (303)
Respiratory Research, 2005 Background Inflammation in the airways and lung parenchyma underlies fixed airway obstruction in chronic obstructive pulmonary disease. The exact role of smoking as promoting factor of inflammation in chronic obstructive pulmonary disease is not clear ...
Willemse Brigitte WM +4 more
doaj +1 more source
Chronic obstructive pulmonary disease: management of chronic disease [PDF]
Medicine, 2012 Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, affecting an estimated 3 million people in the UK. The most common cause is tobacco smoke. Patients with COPD experience a high symptom burden, worsened during disease instability (termed exacerbations or ‘lung attacks’), and a multidisciplinary approach should ...
Russell, R, Norcliffe, J, Bafadhel, M
openaire +4 more sources
Changing patterns in long-acting bronchodilator trials in chronic obstructive pulmonary disease.
, 2011 Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Developments in the understanding of COPD have led to standard guidelines for diagnosis, treatment, and spirometry assessments, which have in turn ...
James Donohue +5 more
core +1 more source
Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial [PDF]
, 2000 Objectives To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease.
Spencer, S +12 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Models of chronic obstructive pulmonary disease
, 2004 Chronic obstructive pulmonary disease (COPD) is a major global health problem and is predicted to become the third most common cause of death by 2020. Apart from the important preventive steps of smoking cessation, there are no other specific treatments ...
David A Groneberg +5 more
core +1 more source
Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease [PDF]
, 2011 Chronic obstructive pulmonary disease (COPD) is a global health problem. The current therapies for COPD are poorly effective and the mainstays of pharmacotherapy are bronchodilators.
Hongwei Yao +3 more
core +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
International Archives of Otorhinolaryngology, 2013 Summary Introduction: Chronic obstructive pulmonary disease is characterized by progressive and partially reversible obstruction of pulmonary airflow.
Marina Rodrigues Bueno Macri +6 more
doaj +1 more source
Pulmonary embolism with chronic obstructive pulmonary disease
Chronic Diseases and Translational Medicine, 2021 AbstractChronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease. The incidence of COPD is growing annually in China, and it is a significant and growing public health burden. Multivariate analysis showed that COPD was one of the independent risk factors for the occurrence of pulmonary embolism (PE), and the ...
Ruohan Yang, Guiqing Liu, Chaosheng Deng
openaire +3 more sources