Results 61 to 70 of about 305,626 (215)

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel   +13 more
wiley   +1 more source

Asthma and chronic obstructive pulmonary disease overlap: asthmatic chronic obstructive pulmonary disease or chronic obstructive asthma?

open access: yesTherapeutic Advances in Respiratory Disease, 2016
Asthma and chronic obstructive pulmonary disease (COPD) are different disease entities. They are both clinical diagnoses, with diagnostic tools to discriminate between one another. However, especially in older patients (>55 years) it seems more difficult
Annelies Slats, Christian Taube
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Microbiological features of bronchial asthma and chronic obstructive pulmonary disease during remission

open access: yesКлиническая практика, 2018
Background: Bronchial asthma and chronic obstructive pulmonary disease are currently the fifth leading cause of death in the world. The combination of bronchial asthma and chronic obstructive pulmonary disease seems to be a unique disease resulting from ...
M. Yu. Smirnova-Saprytskaya   +4 more
doaj   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Association between Psoriasis and Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.

open access: yesPLoS ONE, 2015
Psoriasis is considered a systemic inflammatory disorder. Previous studies have reported conflicting positive or negative correlations between psoriasis and chronic obstructive pulmonary disease. We performed a meta-analysis to determine whether there is
Xin Li   +8 more
doaj   +1 more source

FORECASTING CORONARY EVENTS BASED ON THE ANALYSIS OF THE DYNAMICS OF MORPHOFUNCTIONAL PARAMETERS OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN THE NORTH

open access: yesАрхивъ внутренней медицины, 2018
In modern society, chronic obstructive pulmonary disease has been isolated relatively recently in an independent nosological unit and, along with cardiovascular diseases, constitutes the leading group of  socially significant chronic diseases, being one ...
D. A. Dolgopolova   +2 more
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman   +12 more
wiley   +1 more source

Chronic Obstructive Pulmonary Disease as a Cardiovascular Diseases Risk Factor in Erbil

open access: yesErbil Journal of Nursing and Midwifery, 2019
Background and objectives: Chronic obstructive pulmonary disease (COPD) has been reported as the most common cause of morbidity and mortality all over the world.
Goran Abubaker Osman   +4 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy