Results 231 to 240 of about 1,719,335 (360)

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Coactosin‐Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation

Advanced Science, EarlyView.
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan, Zhengnan Ren, Binbin Li, Wenjie Liang, Yang Luo, Qin Yang, He Liu, Xiaoliang Dong, Haizhi Tian, Huimin Zou, Bengt Samuelsson, Olof Rådmark, Jia Sun   +12 more
wiley   +1 more source

A comment on "Association between oral microbiome diversity and chronic obstructive pulmonary disease in the US population". [PDF]

J Transl Med
Luo M, Xin K, Luo T.
europepmc   +1 more source

Effect of Highly Concentrated Oxygen Inhalation (I) : CLINICAL STUDIES OF THE PULMONARY FUNCTION IN PATIENTS OF HEART DISEASE AND RESPIRATORY RESPONSE AND CIRCULATORY DYNAMICS OF PATIENTS UNDER

, 1959
T Miyakawa
openalex   +2 more sources

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

Advanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao, Hui Zhang, Jingyi Wu, Yaqi Huang, Xiangnan Li, Meijia Wang, Shuming Wang, Jiaofeng Wang, Jie Chen, Zhi jun Bao, Li Jin, Xiaofeng Wang, Zixin Hu, Shuai Jiang, Yi Li   +14 more
wiley   +1 more source

Nutritional Support of Chronic Obstructive Pulmonary Disease. [PDF]

Nutrients
Simon P, Török É, Szalontai K, Kari B, Neuperger P, Zavala N, Kanizsai I, Puskás LG, Török S, Szebeni GJ.   +9 more
europepmc   +1 more source

A Clinical Patho-Physiological Study of Coronary Circulation and Myocardial Gas Metabolism in Patients with Cardiovascular Disease and Pulmonary Disease

, 1959
Satoru Ogawa, Takayuki Mizuno, SHIGEYUKI TANIGUCHI, Akira Mito, Ichiro Seki   +4 more
openalex   +2 more sources

CARDIOGRAPHIC ASSESSMENT OF PULMONARY VASCULAR DISEASE IN VENTRICULAR SEPTAL DEFECT [PDF]

, 1962
A.S. Hollman, J. F. Goodwin, Lofty L. Basta   +2 more
openalex   +1 more source

Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects

Advanced Science, EarlyView.
Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu, Ming Yi, Ji Chen, Jing Zhang, Xiaobin Ma, Xiaojun Zhang, Liang Zeng, Yan Xue, Haimei Wen, Yujiao Deng, Pengfei Zhou, Kongming Wu, Huafeng Kang, Zhijun Dai   +13 more
wiley   +1 more source

Multi-omics characterization of early chronic obstructive pulmonary disease. [PDF]

Respir Res
Li B, Liu J, Cao Y, Wang Y, Wu S, Hu H, Xiao X, Hu J, Wang Q, Wu J, Luo L, Liu Y, Tang Q, Xing Y, Zhang T, Zhou J, Wang L, Yang J, Wang J, Wang C.   +19 more
europepmc   +1 more source