Results 231 to 240 of about 1,301,573 (319)

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li   +14 more
wiley   +1 more source

Alpha-1 Antitrypsin Deficiency-Associated Chronic Obstructive Pulmonary Disease. [PDF]

open access: yesMedicina (Kaunas)
Fouka E   +4 more
europepmc   +1 more source

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

open access: yesAdvanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen   +8 more
wiley   +1 more source

A Real-World Evaluation of Therapeutic Inertia in Patients with Severe Uncontrolled Chronic Obstructive Pulmonary Disease. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis
Calle Rubio M   +5 more
europepmc   +1 more source

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

open access: yesAdvanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei   +3 more
wiley   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan   +6 more
wiley   +1 more source

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