Results 271 to 280 of about 11,770,891 (406)

CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover

open access: yesAdvanced Science, EarlyView.
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang   +16 more
wiley   +1 more source

Chronic Obstructive Pulmonary Disease in Hemodialysis Patients: Prevalence, Morbidity and Mortality Risks. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis
Wand O   +7 more
europepmc   +1 more source

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan   +20 more
wiley   +1 more source

Efficacy and safety of gemifloxacin in the treatment of acute exacerbation of chronic obstructive pulmonary disease: open prospective multicentre study

open access: hybrid, 2008
С. Н. Авдеев   +5 more
openalex   +2 more sources

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

open access: yesAdvanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan   +9 more
wiley   +1 more source

Ichthyol in Pulmonary Disease

open access: green, 1904
NULL AUTHOR_ID
openalex   +1 more source

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

open access: yesAdvanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy