Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha +13 more
wiley +1 more source
Treating chronic obstructive pulmonary disease with ensifentrine: a systematic review. [PDF]
Almuntashiri S +8 more
europepmc +1 more source
Microvascular Health as a Key Determinant of Organismal Aging
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini +4 more
wiley +1 more source
Global trends and research hotspots in pulmonary rehabilitation for chronic obstructive pulmonary disease: a bibliometric analysis (2011-2024). [PDF]
Yuan Q, Zeng Z.
europepmc +1 more source
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang +8 more
wiley +1 more source
Productivity benefits of chronic obstructive pulmonary disease prevention in China. [PDF]
Zhu Y, Li Z, Chen S, Huang X, Huang Y.
europepmc +1 more source
Is telerehabilitation effective for treating infectious pulmonary diseases such as COVID-19 following late hospital discharge? A randomized blinded clinical trial [PDF]
Marília Simões Lopes Quintana +6 more
openalex +1 more source
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source
Nrf2 signaling in chronic obstructive pulmonary disease: regulation of ferroptosis and therapeutic implications. [PDF]
Gao Q +6 more
europepmc +1 more source

