Prediction of disease progression, treatment response and dropout in chronic obstructive pulmonary disease (COPD). [PDF]
, 2014 Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced expiratory volume in one second (FEV1), numerous causes are known to contribute to ...
Danhof, M +6 more
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Pathogenesis of chronic obstructive pulmonary disease [PDF]
, 2005 The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
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Cavitary Pulmonary Disease [PDF]
Clinical Microbiology Reviews, 2008 SUMMARYA pulmonary cavity is a gas-filled area of the lung in the center of a nodule or area of consolidation and may be clinically observed by use of plain chest radiography or computed tomography. Cavities are present in a wide variety of infectious and noninfectious processes.
L Beth, Gadkowski, Jason E, Stout
openaire +2 more sources
The patient experience of pulmonary hypertension: a large cross-sectional study of UK patients
BMC Pulmonary Medicine, 2019 Background Pulmonary Hypertension Association UK (PHA-UK) is the only charity in the UK especially for people affected by pulmonary hypertension (PH).
Iain Armstrong +6 more
doaj +1 more source
Psychosocial Need Analysis of Patients with Pulmonary Tuberculosis. [PDF]
, 2014 Pulmonary tuberculosis (TB) is a chronic pulmonary disease impacted on physical and psychosocial of the patients. However, to date, the goverment’s programs has not address the psychososial problem of the patients yet.
Hernawati, T. (Taty) +3 more
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Protein engineering to develop a redox insensitive endothelial nitric oxide synthase
Redox Biology, 2014 The zinc tetrathiolate (ZnS4) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with ...
Ruslan Rafikov +9 more
doaj +1 more source
Respiratory Research, 2022 Background Trimethylamine N-oxide (TMAO), the gut microbiota-dependent metabolite, is a potential biomarker in several cardiovascular diseases. However, no study has investigated its value in pulmonary hypertension (PH).
Yicheng Yang +10 more
doaj +1 more source
Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology
Biomedicines, 2023 Chronic thromboembolic pulmonary disease results from the incomplete resolution of thrombi, leading to fibrotic obstructions. These vascular obstructions and additional microvasculopathy may lead to chronic thromboembolic pulmonary hypertension (CTEPH ...
Hakim Ghani, Joanna Pepke-Zaba
doaj +1 more source
Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]
, 2016 Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed +5 more
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Tracking dyspnea up to supplemental oxygen prescription among patients with pulmonary fibrosis
BMC Pulmonary Medicine, 2017 Background Dyspnea is the hallmark symptom of pulmonary fibrosis. Supplemental oxygen (O2) is prescribed to many patients with pulmonary fibrosis in hopes of alleviating dyspnea and improving physical functioning.
Amy L. Olson +10 more
doaj +1 more source