Results 31 to 40 of about 11,167,208 (428)
Intravenous (i.v.) prostacyclin is the cornerstone treatment in high‐risk pulmonary arterial hypertension (PAH) patients. Selexipag is an orally available prostacyclin receptor agonist.
André Alexandre+7 more
doaj +1 more source
Backgrounds Mounting evidences have highlighted the association between metabolites and cardiovascular diseases. Our previous works have demonstrated that circulating metabolite, trimethylamine oxide, was associated with prognosis of patients with ...
Yicheng Yang+8 more
doaj +1 more source
Nodular Sarcoidosis Masquerading as Cancer. [PDF]
Nodular lung disease is a rare pulmonary manifestation of sarcoidosis and resembles metastatic neoplasm disease. Nodular sarcoidosis is rare, varying from 1.6% to 4% of patients with sarcoidosis.
Singh, Navneet K+3 more
core +2 more sources
A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension [PDF]
Chronic thromboembolic pulmonary hypertension (CTEPH) is caused by recurrent or unresolved pulmonary thromboemboli, leading to perfusion defects and increased arterial wave reflections. CTEPH treatment aims to reduce pulmonary arterial pressure and reestablish adequate lung perfusion, yet patients with distal lesions are inoperable by standard surgical
arxiv +1 more source
MicroRNAs in pulmonary arterial remodeling [PDF]
Pulmonary arterial remodeling is a presently irreversible pathologic hallmark of pulmonary arterial hypertension (PAH). This complex disease involves pathogenic dysregulation of all cell types within the small pulmonary arteries contributing to vascular ...
A Courboulin+137 more
core +2 more sources
Introduction. Legionella is a frequent cause of bacterial pneumonia in patients with AIDS. While multiple organisms have been associated with cavitary pneumonia in this population, Legionella has not. Clinical Case.
Richard Jesse Durrance+3 more
doaj +1 more source
Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia [PDF]
BACKGROUND: Most patients with familial primary pulmonary hypertension have defects in the gene for bone morphogenetic protein receptor II (BMPR2), a member of the transforming growth factor beta (TGF-beta) superfamily of receptors. Because patients with
Alessandra Manes+25 more
core +1 more source
The nature of small-airway obstruction in chronic obstructive pulmonary disease.
BACKGROUND Chronic obstructive pulmonary disease (COPD) is a major public health problem associated with long-term exposure to toxic gases and particles. We examined the evolution of the pathological effects of airway obstruction in patients with COPD.
J. Hogg+10 more
semanticscholar +1 more source
Under pressure: pulmonary hypertension associated with left heart disease. [PDF]
© ERS 2015.Pulmonary hypertension (PH) associated with left heart disease (PH-LHD) is the most common type of PH, but its natural history is not well understood.
Farber, HW, Gibbs, S
core +2 more sources
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.
BACKGROUND Long-acting beta-agonists and inhaled corticosteroids are used to treat chronic obstructive pulmonary disease (COPD), but their effect on survival is unknown.
P. Calverley+7 more
semanticscholar +1 more source