Results 31 to 40 of about 1,149,004 (269)
Relationship between ID1 and EGFR-TKI Resistance in Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer, 2016 Background and objective Non-small cell lung cancer (NSCLC) presents the highest morbidity and mortality among malignant tumors worldwide. The overall effective rate of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is 30% to 40 ...
Yuchen BAO +7 more
doaj +1 more source
Case Reports in Pulmonology, 2021 Introduction. Legionella is a frequent cause of bacterial pneumonia in patients with AIDS. While multiple organisms have been associated with cavitary pneumonia in this population, Legionella has not. Clinical Case.
Richard Jesse Durrance +3 more
doaj +1 more source
Progress in the Metabolomics of Acute Coronary Syndrome
Reviews in Cardiovascular Medicine, 2023 Acute coronary syndrome (ACS) is a severe type of coronary heart disease (CHD) with increasing prevalence and significant challenges for prevention and treatment.
Fu Zhang +7 more
doaj +1 more source
Autophagy in Pulmonary Diseases [PDF]
American Journal of Respiratory and Critical Care Medicine, 2016 Abstract The pathogenesis of pulmonary diseases is often complex and characterized by multiple cellular events, including inflammation, cell death, and cell proliferation. The mechanisms by which these events are regulated in pulmonary diseases remain poorly understood.
Kiichi, Nakahira +2 more
openaire +2 more sources
The patient experience of pulmonary hypertension: a large cross-sectional study of UK patients
BMC Pulmonary Medicine, 2019 Background Pulmonary Hypertension Association UK (PHA-UK) is the only charity in the UK especially for people affected by pulmonary hypertension (PH).
Iain Armstrong +6 more
doaj +1 more source
Autophagy and pulmonary disease [PDF]
Therapeutic Advances in Respiratory Disease, 2019 Autophagy is a process of cell self-renewal that is dependent on the degradation of the cytoplasmic proteins or organelles of lysosomes. Many diseases, such as metabolic diseases, cancer, neurodegenerative diseases, and lung diseases, have been confirmed to be associated with elevated or impaired levels of autophagy.
Shi-xia Liao +5 more
openaire +3 more sources
Protein engineering to develop a redox insensitive endothelial nitric oxide synthase
Redox Biology, 2014 The zinc tetrathiolate (ZnS4) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with ...
Ruslan Rafikov +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks +5 more
wiley +1 more source
Life Sciences, 2019 Toll-like receptors (TLRs) comprise a clan of proteins involved in identification and triggering a suitable response against pathogenic attacks. As lung is steadily exposed to multiple infectious agents, antigens and host-derived danger signals, the inhabiting stromal and myeloid cells of the lung express an aggregate of TLRs which perceive the ...
Arora, Shweta +10 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley +1 more source