Results 101 to 110 of about 258,909 (307)

The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs [PDF]

, 2012
The correction of hypovolemia with acellular fluids results in acute normovolemic anemia. Whether the choice of the infusion fluid has an impact on the maintenance of oxygen (O2) supply during acute normovolemic anemia has not been investigated so far ...
Habler, Oliver, Horn, Oliver, Kertscho, Harry, Kutschker, Saskia, Lossen, Mischa, Pape, Andreas, Stein, Peter, Zwissler, Bernhard   +7 more
core   +2 more sources

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source

CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison

, 2019
Large, labeled datasets have driven deep learning methods to achieve expert-level performance on a variety of medical imaging tasks. We present CheXpert, a large dataset that contains 224,316 chest radiographs of 65,240 patients.
Ball, Robyn, Chute, Chris, Ciurea-Ilcus, Silviana, Haghgoo, Behzad, Halabi, Safwan S., Irvin, Jeremy, Jones, Ricky, Ko, Michael, Langlotz, Curtis P., Larson, David B., Lungren, Matthew P., Marklund, Henrik, Mong, David A., Ng, Andrew Y., Patel, Bhavik N., Rajpurkar, Pranav, Sandberg, Jesse K., Seekins, Jayne, Shpanskaya, Katie, Yu, Yifan   +19 more
core   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart

Animal Models and Experimental Medicine, EarlyView.
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang, Haifeng Jiang, Zhen Xu, Tingyu Dong, Xiaoyi Liu, Shangxue Yan, Jiajie Kuai, Yan Chang, Wei Wei   +8 more
wiley   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Fatal Complication in Two Cases of Intubation due to Obstructive Respiratory Failure: Negative Pressure Pulmonary Edema

Journal of Pediatric Emergency and Intensive Care Medicine, 2018
Negative pressure pulmonary edema is a rare but potentially fatal complication that can be seen after upper and lower respiratory tract obstructions. In this paper, we aimed to present two cases of negative pressure pulmonary edema in a 18-months-old ...
Ülkem Koçoğlu Barlas, Hasan Serdar Kıhtır, Mey Talip Petmezci, Nihal Akçay, Esra Şevketoğlu   +4 more
doaj   +1 more source

Neurogenic pulmonary edema

Journal of Osteopathic Medicine, 1993
Abstract Neurogenic pulmonary edema is a potential complication of severe central nervous system insult. In the patient described, neurogenic pulmonary edema resulted from gunshot injuries to the head. Aggressive supportive care and intravenous administration of dopamine successfully resolved this pulmonary complication.
C F, Locke, R F, Sing, R F, Sing
openaire   +2 more sources

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

Animal Models and Experimental Medicine, EarlyView.
Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li, Fansen Lin, Hongzhi Gao, Yun Zhao, Yuqi Liu   +4 more
wiley   +1 more source

Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti‐inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies

Animal Models and Experimental Medicine, EarlyView.
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Nusrat Jahan Moon, Mahathir Mohammad, Md. Jahirul Islam Mamun, Fahmina Binty Azim Nova, Nazmul Hasan Eshaque, Md. Hossain Rasel, Zobayed Islam, Md. Mahmudul Hasan, Md. Liakot Ali, Md. Tanvir Chowdhury, S. M. Moazzem Hossen   +10 more
wiley   +1 more source