Results 91 to 100 of about 794,216 (288)

Forma rara de edema pulmonar agudo: a propósito de um caso clínico

Revista Portuguesa de Cardiologia, 2011
Resumo: Apresentamos o caso de um homem de 21 anos, que foi submetido a apendicectomia sob anestesia geral e que imediatamente após a extubação desencadeou quadro de edema pulmonar agudo.
José Ricardo, Maria José Anaya, Mário Barbosa, Nelson André, Pedro Magno, José Morais, Gonçalo Proença, Carlos Rabaçal, Victor Gil   +8 more
doaj   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

ROCK2 and MYLK variants and high-altitude pulmonary edema

, 2016
Gaurav Sikri, Srinivasa Bhattachar Department of Physiology, Armed Forces Medical College, Pune, Maharashtra, IndiaWe have read the article titled “ROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with ...
Sikri G, Bhattachar S
core  

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

Advanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum, Shenja Buchholz, Hanna Schifter, Sabine Ameling, Leif Steil, Ben Lewin Becker, Elke Hammer, Georg Homuth, Uwe Völker, Barbara M. Bröker, Lukas Zierke, Frank Ulrich Weiss, Juliane Glaubitz, Matthias Sendler   +13 more
wiley   +1 more source

Pulmonary edema and ascorbic acid loss

, 1975
Loss of ascorbic acid from the lungs and pulmonary edema were produced in mice by the i.v. injection of either adrenaline or noradrenaline (5 μmol/kg).
C. C. Kratzing, R. J. Willis, Kratzing C.C., Willis R.J.   +3 more
core   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Fatal Complication in Two Cases of Intubation due to Obstructive Respiratory Failure: Negative Pressure Pulmonary Edema

Journal of Pediatric Emergency and Intensive Care Medicine, 2018
Negative pressure pulmonary edema is a rare but potentially fatal complication that can be seen after upper and lower respiratory tract obstructions. In this paper, we aimed to present two cases of negative pressure pulmonary edema in a 18-months-old ...
Ülkem Koçoğlu Barlas, Hasan Serdar Kıhtır, Mey Talip Petmezci, Nihal Akçay, Esra Şevketoğlu   +4 more
doaj   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Clinical and radiologic features of pulmonary edema

, 1999
Pulmonary edema may be classified as increased hydrostatic pressure edema, permeability edema with diffuse alveolar damage (DAD), permeability edema without DAD, or mixed edema. Pulmonary edema has variable manifestations. Postobstructive pulmonary edema
Schnyder, P., Vock, P., Wicky, S., Capasso, P., Revelly, J. P., Gluecker, T., Chiolero, R., Gudinchet, F., Schaller, M. D.   +8 more
core   +1 more source