Results 121 to 130 of about 1,487,555 (351)
Elexacaftor–Tezacaftor–Ivacaftor Improves Sinonasal Outcomes in Young Children With Cystic Fibrosis
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Severe chronic rhinosinusitis (CRS) is a near universal manifestation of cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor (ETI) is an oral, small molecule, highly effective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector–potentiator drug.
Amanda L. Stapleton +10 more
wiley +1 more source
Pulmonary Circulation, 2020 This study investigated whether dilated bronchial arteries are associated with reperfusion pulmonary edema in patients with chronic thromboembolic pulmonary hypertension.
Yumiko Ikubo +18 more
doaj +1 more source
Experimental study of a novel mouse model of tibial shaft fracture combined with blunt chest trauma
Animal Models and Experimental Medicine, EarlyView.Novel animal models showed the same pathological mechanism and imaging characteristics as those of patients with multiple trauma. Our model is useful for studying whether blocking or interfering with cytokine responses is beneficial in the treatment of multiple trauma patients.
Bing Zhang +5 more
wiley +1 more source
Journal of Research in Pharmacy Practice, 2016 Objective: Methadone poisoning is common in our society, mainly in drug addicts. One of its lethal complications is pulmonary edema. Therefore, we evaluated the prevalence of pulmonary edema in the deceased cases with methadone poisoning and its possible
Nastaran Eizadi-Mood +4 more
doaj +1 more source
Abnormality Detection and Localization in Chest X-Rays using Deep Convolutional Neural Networks [PDF]
arXiv, 2017 Chest X-Rays (CXRs) are widely used for diagnosing abnormalities in the heart and lung area. Automatically detecting these abnormalities with high accuracy could greatly enhance real world diagnosis processes. Lack of standard publicly available dataset and benchmark studies, however, makes it difficult to compare various detection methods. In order to
arxiv
Anesthesia and Analgesia, 2013 The endothelial glycocalyx is a dynamic layer of macromolecules at the luminal surface of vascular endothelium that is involved in fluid homeostasis and regulation.
Stephen R. Collins +3 more
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao +6 more
wiley +1 more source
Croup-induced Postobstructive Pulmonary Edema
Kaohsiung Journal of Medical Sciences, 2010 Postobstructive pulmonary edema is life-threatening, and results from a sudden episode of upper airway obstruction. Croup is generally thought to be a benign condition, but occasionally it can develop into postobstructive pulmonary edema.
I-Chen Chen +5 more
doaj +1 more source
Acute inflammatory response to contrast agent aspiration and its mechanisms in the rat lung. [PDF]
, 2019 Objectives/hypothesisContrast agent (CA) aspiration is an established complication of upper gastrointestinal and videofluoroscopic swallow studies. The underlying molecular biological mechanisms of acute response to CA aspiration in the respiratory ...
Belafsky, Peter C +6 more
core +1 more source
Establishment of rat model for aspiration pneumonia and potential mechanisms
Animal Models and Experimental Medicine, EarlyView.Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu +7 more
wiley +1 more source