Results 71 to 80 of about 1,419,137 (340)

Vascular homeostasis at high-altitude: role of genetic variants and transcription factors

open access: yesPulmonary Circulation, 2020
High-altitude pulmonary edema occurs most frequently in non-acclimatized low landers on exposure to altitude ≥2500 m. High-altitude pulmonary edema is a complex condition that involves perturbation of signaling pathways in vasoconstrictors, vasodilators,
Neha Chanana   +3 more
doaj   +1 more source

Establishment of rat model for aspiration pneumonia and potential mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu   +7 more
wiley   +1 more source

Resolution of pulmonary edema. Thirty years of progress.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2014
In the last 30 years, we have learned much about the molecular, cellular, and physiological mechanisms that regulate the resolution of pulmonary edema in both the normal and the injured lung.
M. Matthay
semanticscholar   +1 more source

Negative pressure pulmonary edema: a case report

open access: yesBMC Anesthesiology, 2019
Background The negative pressure pulmonary edema is rare clinical situation which caused mainly by upper airway obstruction. However except upper airway obstruction, there may be other pathophysiological disorders making patients more vulnerable to ...
Jun Xiong, Yongxing Sun
doaj   +1 more source

An optimized perfusate for enhanced rat ex vivo lung perfusion and lung transplant models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We explored a low‐cost and efficient perfusate composition for use in rat ex vivo lung perfusion (EVLP) and lung transplant models. This perfusate demonstrates better biocompatibility, likely due to a reduction in immune responses associated with high doses of xenogenic proteins, resulting in less lung injury posttransplantation.
Jie Zhang, Xuanlin Zhang, Jianxing He
wiley   +1 more source

Understanding negative pressure pulmonary edema

open access: yesIntensive Care Medicine, 2014
Negative pressure pulmonary edema (NPPE) is a form of noncardiogenic pulmonary edema (PE) that results from the generation of high negative intrathoracic pressure (NIP) needed to overcome upper airway obstruction (UAO).
M. Lemyze, J. Mallat
semanticscholar   +1 more source

Neurogenic Pulmonary Edema (A Case Report)

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2012
Neurogenic pulmonary edema is a life threatening complication of severe central nervous system injury. The most common cause of neurogenic pulmonary edema is subarachnoid hemorrhage followed by head trauma and epilepsy. The rare causes are cervical spine
Funda Gümüş   +5 more
doaj   +1 more source

Dual‐energy X‐ray absorptiometry for detecting neurogenic pulmonary edema in a mouse model of subarachnoid hemorrhage

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using a murine model of SAH, brain magnetic resonance imaging (MRI) was performed to confirm subarachnoid clot formation in the T2*‐weighted images sequence (left). Chest micro‐CT and DXA were performed to measure, respectively, the Hounsfield units (HU) and lean mass (LM) (middle) in order to test their relationship and ability to detect post‐SAH NPE (
Tatsushi Mutoh   +3 more
wiley   +1 more source

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

Immersion Pulmonary Edema in Female Triathletes

open access: yesPulmonary Medicine, 2011
Pulmonary edema has been reported in SCUBA divers, apnea divers, and long-distance swimmers however, no instances of pulmonary edema in triathletes exist in the scientific literature.
Eric A. Carter, Michael S. Koehle
doaj   +1 more source

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