Results 81 to 90 of about 17,400 (182)
Management of patients with high-risk pulmonary embolism: a narrative review
High-risk pulmonary embolism (PE) is a life-threatening disorder associated with high mortality and morbidity. Most deaths in patients with shock occur within the first few hours after presentation, and rapid diagnosis and treatment is therefore ...
Takeshi Yamamoto
doaj +1 more source
ABSTRACT Ceftazidime/avibactam (CAZ‐AVI) is an important therapeutic option for multidrug‐resistant (MDR) Pseudomonas aeruginosa infections; however, hypersensitivity reactions may preclude its use and create significant therapeutic challenges. We report a 21‐year‐old woman with cystic fibrosis and recurrent MDR P.
Zuoren Zhou +6 more
wiley +1 more source
Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba +2 more
wiley +1 more source
ABSTRACT Background Low‐flow vascular malformations (LFVMs) of the head and neck, including venous and lymphatic malformations, represent a heterogeneous group of congenital anomalies frequently requiring intervention due to functional and esthetic impairment.
Riccardo Nocini +6 more
wiley +1 more source
An Italian cartography of VEXAS‐related thrombosis
Abstract Thrombotic events (TEs) occur in up to 40% of patients with vacuoles, E1 enzyme, X‐linked, autoinflammatory, and somatic (VEXAS) syndrome, but data on its clinical‐genomics features and anticoagulation strategies are limited. To gain more insight into this, we conducted a two‐step study evaluating the prevalence and outcome of TE in VEXAS ...
Giorgia Ranucci +42 more
wiley +1 more source
ABSTRACT Background and Aims Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent whose clinical utility is significantly constrained by severe side effects, most notably DOX‐induced cardiotoxicity (DIC). Pathophysiological mechanisms of DIC include oxidative stress, mitochondrial dysfunction, programmed cell death, and inflammation ...
Ali Mirzaei +8 more
wiley +1 more source
High- and intermediate-risk pulmonary embolism in pediatric tertiary care centers in the Netherlands
Background: Pulmonary embolism (PE) response teams are increasingly used in adult care to improve severe PE management. Understanding the epidemiology, treatment, and outcomes of severe PE in children is crucial to assessing the need for pediatric PE ...
C.A.M. (Karlijn) van Balkom +6 more
doaj +1 more source
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx +9 more
wiley +1 more source
In this meta‐analysis of 2 775 adult ECMO patients from non‐randomized studies, direct thrombin inhibitors and low‐molecular‐weight heparins demonstrated a favorable efficacy and safety profile over unfractionated heparin. These findings suggest them to be effective alternatives to unfractionated heparin, underscoring the urgent need for randomized ...
Vincenz Scharner +7 more
wiley +1 more source
Effect of pulmonary embolism response team on advanced therapies administered: The University of Michigan experience. [PDF]
Ardeshna NS +8 more
europepmc +1 more source

