Results 211 to 220 of about 64,581 (287)

Exome‐based genotype‐first reverse phenotyping using structured electronic health record data identifies novel SERPINA1 variants associated with liver markers and demonstrates a dominant effect for specific variants on liver phenotype

open access: yesHepatology Research, Volume 55, Issue 7, Page 1075-1092, July 2025.
Overview of the exome‐based genotype‐first reverse phenotyping approach targeting SERPINA1. The schematic illustrates key pathways, including cytolysis, cholestasis, and liver synthesis, alongside clinical and biological phenotyping through data extraction and an exome‐wide association approach.
Maël Silva Rodriguez   +11 more
wiley   +1 more source

Pulmonary Emphysema and Proteolysis 1986 [PDF]

open access: bronze, 1987
Charles Mittman, Joseph C. Taylor
openalex   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

open access: yesImmunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma   +2 more
wiley   +1 more source

Impact of radiomics features, pulmonary emphysema score and muscle mass on the rate of pneumothorax and chest tube insertion in CT-guided lung biopsies. [PDF]

open access: yesRespir Res
Leonhardi J   +10 more
europepmc   +1 more source

Impaired Angiotensin Conversion and Bradykinin Clearance in Experimental Canine Pulmonary Emphysema [PDF]

open access: bronze, 1981
S. Alex Stalcup   +6 more
openalex   +1 more source

A Qualitative Exploration of Healthcare Workers' Experiences of End of Life Care for People With an Intellectual Disability

open access: yesJournal of Advanced Nursing, Volume 81, Issue 7, Page 3972-3986, July 2025.
ABSTRACT Aim To explore healthcare workers' experiences of end of life care for people with an intellectual disability. Design A descriptive qualitative study. Method Semi‐structured interviews were conducted with 28 healthcare workers who cared for older people with an intellectual disability at their end of life.
Mary McCarron   +3 more
wiley   +1 more source

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