Results 71 to 80 of about 15,984 (194)

The Therapeutic Potential of Andrographolide and Its Derivatives in Inflammatory Diseases

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT Andrographolide, a diterpenoid component found in traditional Chinese medicine Andrographis paniculata, is known as a natural antibiotic and can be used to treat inflammatory lesions of various systemic diseases. In recent years, andrographolide derivatives have been continuously synthesized and have shown good anti‐inflammatory ...
Xiaoqin Shan   +7 more
wiley   +1 more source

Correlation of lower respiratory tract inflammation with changes in lung function and chest roentgenograms in patients with untreated tropical pulmonary eosinophilia [PDF]

open access: yes, 1991
Forty-one patients with untreated tropical pulmonary eosinophilia (TPE) were studied to determine whether there was any relationship between lower respiratory tract inflammation and either changes in lung function or abnormalities in chest ...
Kuppurao, K V   +3 more
core  

Discontinuation of Oral Glucocorticoids and Achievement of Remission in Patients With Eosinophilic Granulomatosis With Polyangiitis Treated With Benralizumab or Mepolizumab

open access: yesACR Open Rheumatology, Volume 7, Issue 9, September 2025.
Objective In the phase 3 head‐to‐head MANDARA study (NCT04157348), benralizumab demonstrated noninferiority to mepolizumab in inducing remission (defined as Birmingham Vasculitis Activity Score [BVAS] of 0 and oral glucocorticoid [OGC] dosage ≤4 mg/day at weeks 36 and 48) in patients with eosinophilic granulomatosis with polyangiitis (EGPA).
Michael E. Wechsler   +9 more
wiley   +1 more source

A Case of Double ANCA‐Negative Granulomatosis With Polyangiitis in an Ethiopian Man: A Diagnostic Challenge in a Resource‐Limited Setting

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
Double ANCA‐negative Granulomatosis with polyangiitis in an Ethiopian man: a diagnostic challenge highlighting the need for clinicopathologic correlation. ABSTRACT This case highlights the importance of considering ANCA‐negative granulomatosis with polyangiitis (GPA) in patients with nonspecific symptoms with multisystem involvement, including ...
Alazar Sitotaw   +13 more
wiley   +1 more source

Sputum Eosinophil and Macrophage Changes After Aspirin Challenge in Patients With Nonsteroidal Anti‐Inflammatory Drug–Exacerbated Respiratory Disease

open access: yesClinical and Translational Allergy, Volume 15, Issue 9, September 2025.
ABSTRACT Background Induced sputum cell count is crucial for assessing airway inflammatory phenotypes. This study investigated how aspirin‐induced bronchospasm affects sputum cell counts in patients with nonsteroidal anti‐inflammatory drug‐exacerbated respiratory disease (N‐ERD), comparing systemic versus local aspirin administration.
Gabriela Trąd‐Wójcik   +5 more
wiley   +1 more source

Primary cutaneous CD8‐positive aggressive epidermotropic cytotoxic T‐cell lymphoma initially demonstrating near‐complete metabolic response to BV‐CHEP

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Tristen Tze Wei Ng   +5 more
wiley   +1 more source

Innovative Strategies to Reduce Exposure and Expression of the Major Cat Allergen Fel d 1

open access: yesClinical and Translational Allergy, Volume 15, Issue 9, September 2025.
ABSTRACT Background Fel d 1, the primary allergen produced by cats, is a glycoprotein found mainly in their salivary and sebaceous glands. Due to its small size and stability, it easily becomes airborne and adheres to surfaces, posing a persistent problem for allergic individuals. Methods This article reviews innovative strategies aimed at reducing Fel
Simone Colosimo   +7 more
wiley   +1 more source

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 3, Page 765-815, September 2025.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine   +24 more
wiley   +1 more source

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