Results 71 to 80 of about 1,164,895 (313)

Two Sisters with Idiopathic Pulmonary Hemosiderosis

Canadian Respiratory Journal, 2007
Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of diffuse alveolar hemorrhage with unknown etiology. In the present report, the presentations of two sisters are described: one sister had IPH, eosinophilia and a high serum immunoglobulin E (IgE)
Mehmet Gencer, Erkan Ceylan, Muharrem Bitiren, Ahmet Koc   +3 more
doaj   +1 more source

Phase 2 trial of montelukast for prevention of pain in sickle cell disease. [PDF]

, 2020
Cysteinyl leukotrienes (CysLTs) are lipid mediators of inflammation. In patients with sickle cell disease (SCD), levels of CysLTs are increased compared with controls and associated with a higher rate of hospitalization for pain. We tested the hypothesis
Brandow, Amanda, Bryant, Valencia, DeBaun, Michael R, Embury, Stephen H, Field, Joshua J, Kassim, Adetola, Matsui, Neil, Simpson, Pippa, Wilkerson, Karina, Zhang, Liyun   +9 more
core  

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]

, 2015
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC, Jones, PW, Lettis, S, Locantore, N, Pascoe, S, Pavord, ID, Wedzicha, JA   +6 more
core   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]

, 1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB, Erle, DJ, Folkesson, HG, Locksley, RM, Matthay, MA, Warnock, ML, Wiener-Kronish, JP   +6 more
core  

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Eosinophilia Is a Favorable Marker for Pneumonia in Chronic Obstructive Pulmonary Disease [PDF]

Tuberculosis and Respiratory Diseases
Background Patients with chronic obstructive pulmonary disease (COPD) expressing eosinophilia experience slightly fewer episodes of community-acquired pneumonia (CAP), than those without eosinophilia.
Kang-Mo Gu, Jae-Woo Jung, Min-Jong Kang, Deog Kyeom Kim, Hayoung Choi, Young-Jae Cho, Seung Hun Jang, Chang-Hoon Lee, Yeon Mok Oh, Ji Sook Park, Jae Yeol Kim   +10 more
doaj   +1 more source

DRESS Syndrome- Uncommon drug reaction with Common disease treatment - A case report

Journal of Microbiology and Infectious Diseases, 2020
Drug Reaction with Eosinophilia and Systemic symptoms (DRESS syndrome), is a severe adverse reaction associated with diverse collection of drugs, characterized by severe mucocutaneous rash, eosinophilia, fever, lymphadenopathy and extensive systemic ...
Majed Abdul basit Momin, Dr. B Saroj Kumar Prusty, Dr. Yugvaveer k Goud, Dr.Kiran Kumar Ramineni, Dr.Safina Perveen   +4 more
doaj   +1 more source

In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni [PDF]

, 2007
The cytokine interplay during the development of protective immunity to the radiation-attenuated (RA) schistosome vaccine has been extensively characterized over recent years, yet the role of costimulatory molecules in the development of cell-mediated ...
Hamblin, Paul A, Hewitson, James P, Mountford, Adrian P   +2 more
core   +2 more sources

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source