Results 301 to 310 of about 386,415 (318)

Forced oscillation technique in progressive pulmonary fibrosis in a single-center retrospective study. [PDF]

Sci Rep
Denis A, Henket M, Giltay L, Gillet H, Creuen X, Frix AN, Gester F, Louis R, Guiot J.   +8 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Autophagy and exosome dynamics in Radiation-Induced pulmonary fibrosis: the critical role of TRIB3. [PDF]

Respir Res
Li N, Zhao W, Li J, Zhang D, Li K, Yang M, Lu X, Du L, Xu C, Liu Q.   +9 more
europepmc   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis. [PDF]

J Nanobiotechnology
Lee HJ, Lee NK, Kim J, Kim J, Seo D, Shin HE, Kim J, Ahn JH, Kim SN, Kim HS, Park J, Park W, Hong KS, Park CG, Lee W.   +14 more
europepmc   +1 more source

An Integrated Strategy Combining Shotgun Metabarcoding With Conventional Methods for Comprehensive Authentication of Food‐Medicine Homologous Species and Fungal Contamination Detection in Yangyin Qingfei Wan

Food Safety and Health, EarlyView.
This research confirms shotgun metabarcoding accurately identifies YYQFW components, proving its potential for authenticating complex herbal products. Combined with TLC/HPLC, it offers a regulatory approach for food‐medicine homologous ingredients OTC medicines and aids species identification in processed foods with degraded DNA. ABSTRACT OTC medicines
Yu Tian, Lingchao Zeng, Li Tan, Xianming Tang, Xinyi Li, Zhaolei Zhang, Hongye Zhao, Jinxin Liu, Jingyi Zhao, Linchun Shi   +9 more
wiley   +1 more source

Combination Treatment of Timosaponin BII and Pirfenidone Attenuated Pulmonary Fibrosis Through Anti-Inflammatory and Anti-Fibrotic Process in Rodent Pulmonary Fibrosis Model and Cellular Epithelial-Mesenchymal Transition Model. [PDF]

Molecules
Shen X, Zheng Y, Yang H, Liu L, Yu L, Zhang Y, Song X, He Y, Jin R, Jiao J, Gu Z, Zhai K, Nian S, Liu L.   +13 more
europepmc   +1 more source

Controlled Ascent Rate Enhances Autophagy and Mitigates Acute Lung Injury in Rats Exposed to High‐Altitude Hypoxia by Inhibiting Oxidative Stress and Inflammation

Global Challenges, EarlyView.
This study explores how gradual ascent rates reduce acute pulmonary injury in rats exposed to high‐altitude hypoxia by activating autophagy and suppressing oxidative stress and inflammation. Results show that controlled ascent effectively mitigates such injury, highlighting its potential as a preventive strategy.
Kairui Huang, Wenhui Shi, Jiajia Li, Xiaoyan Ma, Jiangwei Liu   +4 more
wiley   +1 more source

Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation. [PDF]

Respir Res
He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H.   +10 more
europepmc   +1 more source

Tracheoesophageal Voicing Following Resistance‐Based Dysphagia Rehabilitation: An Exploratory Multidimensional Assessment

Head &Neck, EarlyView.
ABSTRACT Background This exploratory study investigated tracheoesophageal voicing following 6 weeks of resistance‐based dysphagia rehabilitation with the SEA2.0, using a multidimensional assessment approach. Methods Twenty laryngectomized participants were assessed at T0 (baseline), T1 (after 6 weeks training), and T2 (after 8 weeks rest).
Marise Neijman, Klaske E. van Sluis, Rob J. J. H. van Son, Martijn M. Stuiver, Frans J. M. Hilgers, Michiel W. M. van den Brekel, Maarten J. A. van Alphen, Lisette van der Molen   +7 more
wiley   +1 more source