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Idiopathic pulmonary fibrosis

Expert Review of Respiratory Medicine, 2007
Idiopathic pulmonary fibrosis (IPF; also known as cryptogenic fibrosing alveolitis) is a distinctive type of chronic fibrosing interstitial pneumonia of unknown cause associated with the histological pattern usual interstitial pneumonia (UIP). UIP is a distinct histological pattern observed in IPF but may also be found in other etiologies.
Joseph P, Lynch   +4 more
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Idiopathic Pulmonary Fibrosis

Journal of Thoracic Imaging, 2016
Idiopathic pulmonary fibrosis (IPF) is the most common fibrosing lung disease and is associated with a very poor prognosis. IPF manifests histopathologically as usual interstitial pneumonia (UIP) and as subpleural and basal predominant reticulation with honeycombing on high-resolution computed tomography (HRCT) of the chest.
Maria D, Martin   +2 more
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Idiopathic Pulmonary Fibrosis

Seminars in Respiratory and Critical Care Medicine, 2012
Idiopathic pulmonary fibrosis (IPF) is a specific form of progressive, chronic fibrosing interstitial lung disease occurring primarily in older adults and limited to the lungs. The prognosis is dire, with half of all patients progressing to death from respiratory failure within 3 to 5 years from initial diagnosis. The pathogenesis of IPF is complex and
Jessica M, Adkins, Harold R, Collard
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Diffuse Pulmonary Fibrosis

Postgraduate Medicine, 1959
Diffuse pulmonary fibrosis may have many different causes. When roentgenographs examination reveals evidence of this disease, a detailed history should be obtained and a careful physical examination performed. Extensive laboratory procedures often are necessary. Prognosis and treatment depend on the underlying cause and on complications.
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Idiopathic Pulmonary Fibrosis

New England Journal of Medicine, 2001
Idiopathic pulmonary fibrosis is a rapidly progressive illness of unknown cause characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease. Treatment at present remains largely supportive, with evidence that patients' satisfaction and survival may be improved by referral to centers specializing in the evaluation ...
T J, Gross, G W, Hunninghake
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Idiopathic pulmonary fibrosis

BMJ, 2013
Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF.
Owen J, Dempsey, David, Miller
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Familial pulmonary fibrosis

Revue des Maladies Respiratoires, 2015
The occurrence of pulmonary fibrosis in numerous individuals from the same family suggests a genetic cause for the disease. During the last 10 years, mutations involving proteins from the telomerase complex and from the surfactant system have been identified in association with pulmonary fibrosis.
R, Borie   +5 more
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Oxidative Stress in Pulmonary Fibrosis.

Comprehensive Physiology, 2020
Oxidative stress has been linked to various disease states as well as physiological aging. The lungs are uniquely exposed to a highly oxidizing environment and have evolved several mechanisms to attenuate oxidative stress.
E. Otoupalova   +3 more
semanticscholar   +1 more source

Idiopathic pulmonary fibrosis

Current Opinion in Pulmonary Medicine, 1996
Idiopathic pulmonary fibrosis (IPF), or cryptogenic fibrosing alveolitis as it is known in the United Kingdom and Europe, is perhaps one of the most complex and frustrating pulmonary disorders. The cause of this illness is unknown. Treatment often founders in a mire of discontent, dissatisfaction, and failure. In fact, the philosophic homily "If you do
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Idiopathic Pulmonary Fibrosis

Annual Review of Medicine, 1993
Idiopathic pulmonary fibrosis kills half of its victims within five years of diagnosis. Currently available treatment regimens are disappointing, and the incidence of the disease appears to be increasing. Newer techniques of imaging coupled with laboratory advances in molecular and cellular biology may produce new strategies for modulating the disease ...
openaire   +2 more sources

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