Results 221 to 230 of about 58,255 (295)

Breathing irregularities and postnatal hypoxaemia in an experimental model of essential hypertension

The Journal of Physiology, EarlyView.
Abstract figure legend Neonatal spontaneously hypertensive rats (SHRs) exhibit inherent respiratory dysfunction in early life, including oscillatory breathing patterns and apnoeic events that cause oxygen desaturation and brain hypoxia, in addition to an impaired hypoxic ventilatory response.
Beatriz N. Vieira, Letícia R. Mendes, Sarah G. Mariano, Isabela P. Leirão, Emilson D. Pereira‐Junior, Milede H. Saraiva Paes, Pedro L. Katayama, Daniel B. Zoccal   +7 more
wiley   +1 more source

Endothelial-Epithelial Crosstalk Drives Alveolar-Capillary Barrier Dysfunction in ARDS. [PDF]

J Inflamm Res
Shi J, Qiu M, Han S, Liu X.
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Beyond PaO₂/FiO₂ at altitude: are we correcting the ratio in the wrong direction? [PDF]

Ann Intensive Care
Álvarez-Maldonado P, Torres-Alarcón LA, Cerón-Díaz UW.   +2 more
europepmc   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

The Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu, Asish Dasgupta, Jaskaran Singh Hora, Kuang‐Hueih Chen, Arinjay Banerjee, Stephen L. Archer   +5 more
wiley   +1 more source

The six phases of prolonged veno-venous extracorporeal membrane oxygenator support: a conceptual framework. [PDF]

Crit Care
Hoffman KR, Diehl A, Nixon P, Yong SA, Fan E, Hodgson C, Burrell AJC.   +6 more
europepmc   +1 more source

When the lungs speak to the brain: a new reflex pathway in the neural control of circulation during exercise?

The Journal of Physiology, EarlyView.
Lauro C. Vianna
wiley   +1 more source

Gas exchange and pulmonary stress variations during SCUBA and breath‐hold diving in open seawater

The Journal of Physiology, EarlyView.
Abstract figure legend Healthy, trained divers were studied before, during and after diving in open seawater with different techniques. SCUBA divers (diving to 15 or 40 m with air; cycling at depth) and breath‐hold divers (BHDs; sled‐assisted dives to 15, 25 or 40 m) underwent underwater and surface arterial blood gas (ABG) sampling.
Matteo Paganini, Tommaso Antonio Giacon, Simona Mrakic‐Sposta, Luca Martani, Danilo Cialoni, Lorenzo Zucchi, Vincenzo Maffei, Rosario Cifali, Mariano Marmo, Enrico M Camporesi, Richard E Moon, Gerardo Bosco   +11 more
wiley   +1 more source

Correction: Understanding emotional and practical challenges of initiating oxygen therapy in pulmonary fibrosis: insights from a patient-centered survey. [PDF]

BMC Pulm Med
Drent M, Trapman L, Hennevelt-Leenen M, Grutters JC, Russell AM.   +4 more
europepmc   +1 more source

Ventilatory efficiency: Physiological modelling and mechanistic validation

The Journal of Physiology, EarlyView.
Abstract figure legend From post‐threshold ventilatory linearization to ceiling‐normalized efficiency – conceptual framework underlying ηV̇E$\eta {{\dot{V}}_{\mathrm{E}}}$ Conventional V̇E${{\dot{V}}_{\mathrm{E}}}$–V̇CO2${{\dot{V}}_{{\mathrm{C}}{{{\mathrm{O}}}_2}}}$ slopes are typically derived under submaximal conditions and may become physiologically
Paulo T Muller, Beate Stubbe, Till Ittermann, Erlandson S Ferreira, J A Neder, Ralf Ewert   +5 more
wiley   +1 more source