Results 31 to 40 of about 1,640,993 (346)

Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease

Genome Medicine, 2018
Pulmonary arterial hypertension (PAH) is a rare disease characterized by distinctive changes in pulmonary arterioles that lead to progressive pulmonary arterial pressures, right-sided heart failure, and a high mortality rate.
N. Zhu, C. Welch, Jiayao Wang, Philip Allen, C. Gonzaga‐Jauregui, Lijiang Ma, A. King, U. Krishnan, E. Rosenzweig, D. Ivy, E. Austin, R. Hamid, M. Pauciulo, K. Lutz, W. Nichols, J. Reid, J. Overton, A. Baras, F. Dewey, Yufeng Shen, Yufeng Shen, W. Chung   +21 more
semanticscholar   +1 more source

A stepwise composite echocardiographic score predicts severe pulmonary hypertension in patients with interstitial lung disease

ERJ Open Research, 2018
European Respiratory Society (ERS) guidelines recommend the assessment of patients with interstitial lung disease (ILD) and severe pulmonary hypertension (PH), as defined by a mean pulmonary artery pressure (mPAP) ≥35 mmHg at right heart catheterisation (
Simon Bax, Charlene Bredy, Aleksander Kempny, Konstantinos Dimopoulos, Anand Devaraj, Simon Walsh, Joseph Jacob, Arjun Nair, Maria Kokosi, Gregory Keir, Vasileios Kouranos, Peter M. George, Colm McCabe, Michael Wilde, Athol Wells, Wei Li, Stephen John Wort, Laura C. Price   +17 more
doaj   +1 more source

Adult congenital heart disease: Past, present, future

International Journal of Cardiology Congenital Heart Disease, 2020
The diagnosis and management of congenital heart disease (CHD), the most common inborn defect, has been a tremendous success story of modern medicine. In the 1950s survival of children born with CHD was only approximately 15%, whereas nowadays more than ...
Margarita Brida, Michael A. Gatzoulis
doaj   +1 more source

Cor pulmonale in canine patients

Ciencia Veterinaria, 2020
When we talk about cor pulmonale or pulmonary heart disease we refer to a heart that has been disrupted its structure and, therefore, its function as a result of chronic pulmonary disease.
Roberto Andrés Sosa, Antonela Soledad Mancuso, Roberto Edgardo Sosa   +2 more
doaj   +1 more source

Sildenafil for improving outcomes in patients with corrected valvular heart disease and persistent pulmonary hypertension: a multicenter, double-blind, randomized clinical trial

European Heart Journal, 2017
Aims We aimed to determine whether treatment with sildenafil improves outcomes of patients with persistent pulmonary hypertension (PH) after correction of valvular heart disease (VHD).
Javier Bermejo, R. Yotti, R. García-Orta, P. L. Sánchez‐Fernández, Mario Castaño, J. Segovia-Cubero, P. Escribano-Subías, J. S. San Román, Xavier Borrás, Angel Alonso‐Gómez, J. Botas, M. Crespo-Leiro, Sonia Velasco, A. Bayés-Genís, A. López, R. Muñoz-Aguilera, E. de Teresa, J. González-Juanatey, Arturo Evangelista, T. Mombiela, A. González-Mansilla, J. Elízaga, Javier Martín-Moreiras, J. González-Santos, E. Moreno-Escobar, F. Fernández‐Avilés, Javier Raquel Teresa Ana Jaime José A Esther Candelas Ric Bermejo Yotti Mombiela Gónzález-Mansilla Elízaga G, Javier Bermejo, R. Yotti, T. Mombiela, A. González-Mansilla, J. Elízaga, J. García-Robles, E. Pérez-David, Candelas Pérez del Villar, R. Sanz, Enrique Gutiérrez-Ibañes, M. Vázquez, A. Mur, Y. Benito, P. Martínez‐Legazpi, A. Barrio, A. Vázquez, R. García-Orta, Inés Uribe, M. González, Pedro Luis Sánchez, J. González-Santos, Javier Martín-Moreiras, A. Arribas, M. M. Clemente Lorenzo, Alejandro Diego Nieto, Mario Castaño, A. Pérez de Prado, D. Alonso, J. Segovia-Cubero, M. Gómez-Bueno, I. Sayago Silva, M. Ángel Cavero, P. Escribano-Subías, L. Dominguez, R. Tello de Meneses, M. R. Ruiz Cano, C. Jimenez Lopez-Guarch, J. S. San Román, P. Mota, Xavier Borrás, C. Amorós Galitó, Angel Alonso‐Gómez, M. C. Bello Mora, D. Mesa Rubio, J. Botas, R. Campuzano, M. Crespo-Leiro, R. Marzoa, J. Cuenca, Sonia Velasco, R. Muñoz, V. Suberviola, C. Beltrán Herrera, L. Mora, M. Mar Sarrión, D. Vaqueriza, A. Bayés-Genís, E. Ferrer, J. González-Juanatey, B. Cid, A. M. Monzonís, A. López, J. M. F. Arizón de Prado, M. Santisteban, Arturo Evangelista, D. Garcia-Dorado, E. de Teresa, M. Jiménez-Navarro, Fernando Carrasco Chinchilla, E. Moreno-Escobar, J. Alonso   +97 more
semanticscholar   +1 more source

High-risk pregnancy in a patient with pulmonary arterial hypertension due to congenital heart disease (PAH-CHD) with temporary shunt inversion and deoxygenation

Pulmonary Circulation, 2019
Atrial septal defect (ASD) is one of the most frequent congenital heart diseases (CHD). Up to 10% of adults with an ASD develop pulmonary arterial hypertension (PAH, PAH-CHD) in their lifetime.
Christopher Hohmann, Daniel Dumitrescu, Felix Gerhardt, Tilmann Kramer, Stephan Rosenkranz, Michael Huntgeburth   +5 more
doaj   +1 more source

Application of Artificial Intelligence-Based Auxiliary Diagnosis in Congenital Heart Disease Screening

Anatolian Journal of Cardiology, 2023
Background: To evaluate the application value of artificial intelligence-based auxiliary diagnosis for congenital heart disease. Methods: From May 2017 to December 2019, 1892 cases of congenital heart disease heart sounds were collected for learning ...
Hongbo Yang, Jiahua Pan, Weilian Wang, Tao Guo, Tengyuan Ma   +4 more
doaj   +1 more source

Targeted therapy with phosphodiesterase 5 inhibitors in patients with pulmonary hypertension due to heart failure and elevated pulmonary vascular resistance: a systematic review

Pulmonary Circulation, 2020
Pulmonary Hypertension due to left heart disease is the most common type of Pulmonary Hypertension. Morbidity and mortality significantly increase once Pulmonary Hypertension is present.
Galo M. Sanchez Palacios, Cindy Schmidt, Tammy Wichman   +2 more
doaj   +1 more source

Pulmonary hypertension associated with left heart disease

European Respiratory Journal
Left heart disease (LHD) is the most common cause of pulmonary hypertension (PH), which may be classified further as isolated post-capillary (ipcPH) or combined post- and pre-capillary PH (cpcPH).
B. A. Maron, G. Bortman, Teresa De Marco, Jessica H. Huston, Irene M. Lang, Stephan Rosenkranz, J. Vachiéry, R. Tedford   +7 more
semanticscholar   +1 more source

Congenital Heart Disease and Pulmonary Hypertension

Cardiology Clinics, 2020
Pulmonary hypertension (PH) is common in adults with congenital heart disease and carries fundamental implications for management and prognosis. A high index of suspicion, combined with knowledge of the pathogenesis and pathophysiology of PH, is required to achieve a timely, accurate diagnosis, and appropriate classification and treatment. This article
Constantine, A, Dimopoulos, K, Opotowsky, A   +2 more
openaire   +4 more sources