MicroRNAs in pulmonary arterial remodeling [PDF]
Pulmonary arterial remodeling is a presently irreversible pathologic hallmark of pulmonary arterial hypertension (PAH). This complex disease involves pathogenic dysregulation of all cell types within the small pulmonary arteries contributing to vascular ...
A Courboulin+137 more
core +2 more sources
Encoding Cardiopulmonary Exercise Testing Time Series as Images for Classification using Convolutional Neural Network [PDF]
Exercise testing has been available for more than a half-century and is a remarkably versatile tool for diagnostic and prognostic information of patients for a range of diseases, especially cardiovascular and pulmonary. With rapid advancements in technology, wearables, and learning algorithm in the last decade, its scope has evolved.
arxiv
Diagnosis and Management of Pulmonary Arterial Hypertension [PDF]
Pulmonary arterial hypertension is a rare disease, which requires a high index of suspicion to diagnose when patients initially present. Initial symptoms can be nonspecific and include complaints such as fatigue and mild dyspnea.
Houtchens, Jeanne+2 more
core +3 more sources
Supervised multi-specialist topic model with applications on large-scale electronic health record data [PDF]
Motivation: Electronic health record (EHR) data provides a new venue to elucidate disease comorbidities and latent phenotypes for precision medicine. To fully exploit its potential, a realistic data generative process of the EHR data needs to be modelled. We present MixEHR-S to jointly infer specialist-disease topics from the EHR data.
arxiv
Nitric oxide synthases in infants and children with pulmonary hypertension and congenital heart disease [PDF]
Nitric oxide is an important regulator of vascular tone in the pulmonary circulation. Surgical correction of congenital heart disease limits pulmonary hypertension to a brief period.
A Giaid+30 more
core +3 more sources
Anomalous right pulmonary artery from the aorta [PDF]
Anomalous origin of the right pulmonary artery is a rare form of congenital heart disease. It usually presents in early infancy with heart failure and rapid development of pulmonary hypertension. There are about 131 cases reported in the literature and
Mokhtar, S.A.I.+2 more
core
The case for early use of rapid whole-genome sequencing in management of critically ill infants: late diagnosis of Coffin-Siris syndrome in an infant with left congenital diaphragmatic hernia, congenital heart disease, and recurrent infections. [PDF]
Congenital diaphragmatic hernia (CDH) results from incomplete formation of the diaphragm leading to herniation of abdominal organs into the thoracic cavity. CDH is associated with pulmonary hypoplasia, congenital heart disease, and pulmonary hypertension.
Campo, Miguel Del+7 more
core +2 more sources
Impact of Pulmonary Vascular Resistances in Heart Transplantation for Congenital Heart Disease [PDF]
Congenital heart disease is one of the major diagnoses in pediatric heart transplantation recipients of all age groups. Assessment of pulmonary vascular resistance in these patients prior to transplantation is crucial to determine their candidacy ...
Canter, Charles E, Gazit, Avihu Z
core +2 more sources
The Real Landscape Of Pulmonary Artery Hypertension Associated With Congenital Heart Disease In Vietnam National Heart Institute – Bach Mai Hospital – Vietnam [PDF]
The Real Landscape Of Pulmonary Artery Hypertension Associated With Congenital Heart Disease In Vietnam National Heart Institute – Bach Mai Hospital ...
Huong, Truong Thannh, Nguyen, Thi Duyen
core +2 more sources
Animal models for pah and increased pulmonary blood flow [PDF]
Pulmonary arterial hypertension (PAH), a progressive pulmonary vasoproliferative disorder, is characterized by the development of unique neointimal lesions including concentric laminar intimal fibrosis and plexiform lesions.In PAH associated with ...
Bartelds, Beatrijs+2 more
core +3 more sources