Results 41 to 50 of about 1,820,387 (299)

Rapidly progressive respiratory failure after helminth larvae ingestion

BMC Pulmonary Medicine, 2021
Background Self-administration of helminths has gained attention among patients as a potential but unproven therapy for autoimmune disease. We present a case of rapidly progressive respiratory failure in a patient with systemic sclerosis (SSc) and ...
Anahit A. Zeynalyan, Balaji Kolasani, Chetan Naik, Christopher J. G. Sigakis, Leann Silhan, Susan K. Mathai   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Immune Checkpoint Inhibitor-Associated Myocarditis

JACC: Case Reports, 2020
Immune checkpoint inhibitors (ICIs) can induce immunity-related adverse events. We demonstrate the clinical use of cardiac magnetic resonance and endomyocardial biopsy in the diagnosis and subsequent monitoring of ICI-associated myocarditis, suggesting ...
Grigorios Chatzantonis, MD, Georg Evers, MD, Claudia Meier, MD, Michael Bietenbeck, PhD, Anca Florian, MD, Karin Klingel, MD, Annalen Bleckmann, MD, Ali Yilmaz, MD   +7 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Risk of Coronary Heart Disease in People with Chronic Obstructive Pulmonary Disease: A Meta-Analysis

International Journal of COPD, 2021
Jia-Jie Wang Medical College, Soochow University, Suzhou, Jiangsu Province, People’s Republic of ChinaCorrespondence: Jia-Jie WangMedical College, Soochow University, No.
Wang JJ
doaj  

Pregnancy in a Patient With Tetralogy of Fallot and Borderline Pulmonary Arterial Hypertension

JACC: Case Reports, 2020
Management of pregnancy in patients with complex congenital heart disease and pulmonary arterial hypertension has always been a challenge. We are presenting a patient with complex congenital heart disease and borderline pulmonary arterial hypertension ...
Alexandra A. Frogoudaki, MD, PhD, Sotiria Liori, MD, Penelope Rafouli-Stergiou, MD, PhD, Olga Boleti, MD, Maria Kalantzi, MD, Ignatios Ikonomidis, MD, PhD, John Parissis, MD, PhD   +6 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Distribution, recognition and clinical implications of syndromic conditions in adults with congenital heart disease

Open Heart
Objective Syndromic conditions are frequently associated with congenital heart disease (CHD). Their distribution, recognition and prognostic impact in adults with CHD (ACHD) remain poorly characterised due to limited assessment beyond childhood.Methods ...
Michael A Gatzoulis, Gerhard Paul Diller, Aleksander Kempny, Margarita Brida, Andreas Hoschtitzky, Masahiko Umei, Tuan-Chen Aw   +6 more
doaj   +1 more source

Ventricular rhythm disturbances during computer spirography in patients with stable ischemic heart disease and chronic obstructive pulmonary disease: clinical and functional predictors of occurrence

Zaporožskij Medicinskij Žurnal, 2019
The purpose of the study is to determine the predictors of cardiac rhythm disturbance during spirography in patients with a combination of stable coronary heart disease and chronic obstructive pulmonary disease. Materials and methods.
Yu. M. Mostovoi, L. V. Rasputina, D. V. Didenko, A. O. Dovhan   +3 more
doaj   +1 more source

Understanding the current status of patients with pulmonary hypertension during COVID-19 outbreak: a small-scale national survey from China

Pulmonary Circulation, 2020
Pulmonary hypertension is a chronic disease developing progressively with high mortality. Pulmonary hypertension patients need persistent medical care; however, limited reports focused on them when there was an outbreak of coronavirus disease 2019 in ...
Hongmei Zhou, Gangcheng Zhang, Xiaoxian Deng, Bowen Jin, Qiu Qiu, Menghuan Yan, Xi Wang, Xuan Zheng   +7 more
doaj   +1 more source