Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease [PDF]
Title: Effect of inspiratory pressure support on exercise performance in patients with chronic obstructive pulmonary disease. Purpose: This study examined the effects of a non-invasive ventilator on submaximal and maximal exercise performance in ...
Doggett, Anita
core +2 more sources
Self-management interventions in patients with long-term conditions: a structured review of approaches to reporting inclusion, assessment, and outcomes in multimorbidity [PDF]
Background: Multimorbidity has many potential implications for healthcare delivery, but a particularly important impact concerns the validity of trial evidence underpinning clinical guidelines for individual conditions.
Peter Bower +7 more
core +2 more sources
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
Prediction of disease progression, treatment response and dropout in chronic obstructive pulmonary disease (COPD). [PDF]
Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced expiratory volume in one second (FEV1), numerous causes are known to contribute to ...
Musuamba, F.T. +20 more
core +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Pulmonary regurgitation in congenital heart disease [PDF]
The most important and best described clinical context for pulmonary regurgitation occurs in patients with repaired Tetralogy of Fallot. The first section deals briefly with pulmonary regurgitation in other situations; the remainder of the article deals with tetralogy of Fallot.
Rajiv R, Chaturvedi, Andrew N, Redington
openaire +2 more sources
Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet +11 more
wiley +1 more source
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
The Anatomical Factor in Pulmonary Heart Disease
(1) Out of 415 autopsied cases in Yokufukai Hospital (old people's home) during last 4 years, 28 cases were given the pathological diagnosis of pulmonary heart diseases: 23 cases of pulmonary emphysema, 3 cases of pulmonary tuberculosis, 1 case of pulmonary fibrosis and 1 case of pulmonary embolism. Although the incidence of pulmonary emphysema is much
HARASAWA, Michiyoshi +4 more
openaire +3 more sources
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla +8 more
wiley +1 more source

