Results 1 to 10 of about 104,967 (312)

Nanocrystals based pulmonary inhalation delivery system: advance and challenge [PDF]

Drug Delivery, 2022
Pulmonary inhalation administration is an ideal approach to locally treat lung disease and to achieve systemic administration for other diseases. However, the complex nature of the structural characteristics of the lungs often results in the difficulty ...
Pengfei Yue, Weicheng Zhou, Guiting Huang, Fangfang Lei, Yingchong Chen, Zhilin Ma, Liru Chen, Ming Yang   +7 more
doaj   +2 more sources

Development and evaluation of a novel nebulized dihydromyricetin formulation: enhanced pulmonary delivery and pharmacokinetic properties [PDF]

Respiratory Research
Background Respiratory diseases are a major global health burden, and inhalation therapy offers efficient pulmonary targeting and therapeutic effectiveness.
Kunyan Xu, Jianing Yang, Meng Yan, Dan Li, Wenli Du, Jing Bai, Bai Xiang   +6 more
doaj   +2 more sources

Pulmonary inhalation for disease treatment: Basic research and clinical translations [PDF]

Materials Today Bio
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with few systemic side effects. In addition, it is non-invasive and has good patient compliance, making it a highly promising drug delivery mode. However, there have
Bin Wang, Lin Wang, Qian Yang, Yuming Zhang, Tang Qinglai, Xinming Yang, Zian Xiao, Lanjie Lei, Shisheng Li   +8 more
doaj   +2 more sources

Human re-inhalation ratio under typical conditions [PDF]

E3S Web of Conferences, 2022
Inhaled air quality is directly related to occupants’ health and quality of life. In this study, a numerical breathing thermal manikin was employed, who breathed following a sinusoidal function, with 10 breathing cycles per minute.
Zong Jie, Ai Zhengtao
doaj   +1 more source

Study of the hemodynamic effect of inhaled milrinone versus inhaled nitroglycerin on mechanically ventilated patients with pulmonary hypertension after mitral valve replacement surgeries

Journal of Medicine in Scientific Research, 2022
Introduction Pulmonary arterial hypertension (PH) is commonly found in patients with mitral valve diseases. Most of the drugs used for PH treatment are nonselective pulmonary vasodilators that may cause a modest decrease in pulmonary arterial pressure ...
Ahmed K. Abdel Ghany Hassan, Sherif S A. Sultan, Wafaa El-Sayed Ismail Mostafa, Paula M El-Komos Samaan, Ahmed S F. Saeed   +4 more
doaj   +1 more source

Inhaled pulmonary vasodilators: a narrative review [PDF]

Annals of Translational Medicine, 2021
Pulmonary hypertension (PH) is a severe disease that affects people of all ages. It can occur as an idiopathic disorder at birth or as part of a variety of cardiovascular and pulmonary disorders. Inhaled pulmonary vasodilators (IPV) can reduce pulmonary vascular resistance (PVR) and improve RV function with minimal systemic effects.
Liu, Kai, Wang, Huan, Yu, Shen-Ji, Tu, Guo-Wei, Luo, Zhe   +4 more
openaire   +2 more sources

Validation of the Arabic Severe Respiratory Insufficiency Questionnaire

BMC Pulmonary Medicine, 2021
Background/objectives Assessment of Health-Related Quality of Life (HRQL) in patients with chronic respiratory insufficiency requiring Home Mechanical Ventilation (HMV) requires a valid measurement tool.
Marwan F. Alawieh, Rania N. Bzeih, Mohamad F. El-Khatib, Abla M. Sibai, Lilian A. Ghandour, Salah M. Zeineldine   +5 more
doaj   +1 more source

Improving the Inhalation Technique in Patients with Obstructive Pulmonary Diseases [PDF]

Journal of Biomedical & Clinical Research, 2016
The study aimed to assess the inhalation technique of patients with bronchial asthma/chronic obstructive pulmonary disease (COPD) via an objective method and to evaluate the effect of training in patients with incorrect technique.
Zlatina Ivanova, Nikolay Kyuchukov, Iliya Krachunov, Nikolay Yanev, Pavlina Glogovska, Plamen Pavlov   +5 more
doaj   +3 more sources

Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice

Particle and Fibre Toxicology, 2017
Background The death toll associated with inhaled ambient particulate matter (PM) is attributed mainly to cardio-vascular rather than pulmonary effects. However, it is unclear whether the key event for cardiovascular impairment is particle translocation ...
Koustav Ganguly, Dariusch Ettehadieh, Swapna Upadhyay, Shinji Takenaka, Thure Adler, Erwin Karg, Fritz Krombach, Wolfgang G. Kreyling, Holger Schulz, Otmar Schmid, Tobias Stoeger   +10 more
doaj   +1 more source

Invasive Aspergillus outbreak in inhalation injury: a case presentation and literature review

BMC Infectious Diseases, 2022
Background Invasive pulmonary aspergillosis often occurs in patients with poor immune function, who abuse steroids or broad-spectrum antibiotics, or who use intravenous drugs.
Shengli Liu, Zonghang Li, Jiansheng Zheng, Ning He   +3 more
doaj   +1 more source