Results 201 to 210 of about 104,967 (312)

Can Patient Education Lead the Way? Head‐To‐Head Comparison of EXACT and CERT for Early Recognition of Acute COPD Exacerbations

Respirology, EarlyView.
Daily head‐to‐head comparison of EXACT vs. CERT for early detection of acute COPD exacerbations. Both tools accurately identified exacerbations at diagnosis (AUC≈0.9), but CERT detected worsening one day earlier (p = 0.006). CERT's simplicity and free access support rapid patient self‐monitoring and may enable timely intervention.
Rainer Gloeckl, Paul W. Jones, Daniela Kroll, Inga Jarosch, Tessa Schneeberger, Jing Claussen, Paul Schmidt, Claus F. Vogelmeier, Klaus Kenn, Andreas Rembert Koczulla   +9 more
wiley   +1 more source

From Classics to Nano-Excipients and Biopolymers: Pulmonary Drug Delivery Formulations. [PDF]

Pharmaceutics
Nikou M, Chountoulesi M, Pispas S, Pippa N.   +3 more
europepmc   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

The Effects of Obesity on Lung Physiology, the Prevalence and Severity of Chronic Pulmonary Diseases, and Inhalation Treatment. [PDF]

Drug Des Devel Ther
Fröhlich E.
europepmc   +1 more source

Review for "Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease"

, 2020
Susan Pekarovics
openalex   +1 more source

Body Composition and Muscle Function in Bronchiectasis: A Comparative Longitudinal Study

Respirology, EarlyView.
We compared body composition and muscle function in adults with bronchiectasis versus controls and assessed if leg strength estimates 1‐year outcomes. Patients with bronchiectasis had lower muscle mass, bone density, and leg strength. Reduced leg strength is associated with worse dyspnoea, quality of life, and functional capacity, highlighting the need
Joice Mara de Oliveira, Amber Smith, Paola D. Urroz Guerrero, Laura Cordova Rivera, Dennis Thomas, Vanessa L. Clark, Peter G. Gibson, Vanessa M. McDonald   +7 more
wiley   +1 more source

Inhaled Treprostinil: Improvements in Hemodynamics and Quality of Life for Patients with Pulmonary Arterial Hypertension on Dual or Triple Therapy. [PDF]

J Clin Med
Ikegami S, Hiraide T, Maeda T, Momoi M, Shinya Y, Anzai A, Shiraishi Y, Katsumata Y, Ieda M.   +8 more
europepmc   +1 more source

On the Employment of Inhalations in Consumption and Other Pulmonary Diseases

James Turnbull
openalex   +2 more sources

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

Respirology, EarlyView.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett, Ana L. C. Sayegh, Robert A. Lewis, Tanya J. McWilliams, Sasiharan Sithamparanathan, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

The Discovery of Inhaled Prostanoids for Pulmonary Hypertension. [PDF]

Pulm Circ
Seeger W.
europepmc   +1 more source