Results 21 to 30 of about 104,967 (312)

The effects of different inhalation therapies on less symptomatic chronic obstructive pulmonary disease patients in a Chinese population: a real-world study

Annals of Medicine, 2023
Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) document suggests that patients with chronic obstructive pulmonary disease (COPD) should be divided into a less symptomatic group. Moreover, single-inhaled drugs are recommended
Qing Song, Ling Lin, Aiyuan Zhou, Wei Cheng, Cong Liu, Yating Peng, Zijing Zhou, Yuqin Zeng, Dingding Deng, Dan Liu, Zhiping Yu, Yan Chen, Shan Cai, Ping Chen   +13 more
doaj   +1 more source

Performance of Dry Powder Inhalers with Single Dosed Capsules in Preschool Children and Adults Using Improved Upper Airway Models

Pharmaceutics, 2014
The pulmonary administration of pharmaceutical aerosols to patients is affected by age-dependent variations in the anatomy of the upper airways and the inhalation pattern.
Sandra Lindert, Antje Below, Joerg Breitkreutz   +2 more
doaj   +1 more source

Successful treatment for a patient with chronic thromboembolic pulmonary hypertension comorbid with essential thrombocythemia with the JAK2 V617F mutation by balloon pulmonary angioplasty

Respiratory Medicine Case Reports, 2020
A-71-year-old woman was diagnosed as chronic thromboembolic pulmonary hypertension (CTEPH) accompanied by essential thrombocythemia (ET) with JAK2 V617F mutation.
Tomohiro Yamaguchi, Yasuhiro Izumiya, Hiroya Hayashi, Yoshitaka Ichikawa, Hirotoshi Ishikawa, Atsushi Shibata, Takanori Yamazaki, Minoru Yoshiyama   +7 more
doaj   +1 more source

Do alterations in pulmonary vascular tone result in changes in central blood volumes? An experimental study

Intensive Care Medicine Experimental, 2021
Background The effects of selective pulmonary vascular tone alterations on cardiac preload have not been previously examined. Therefore, we evaluated whether changing pulmonary vascular tone either by hypoxia or the inhalation of aerosolized prostacyclin
Jaap Jan Vos, J. K. Götz Wietasch, Andreas Hoeft, Thomas W. L. Scheeren   +3 more
doaj   +1 more source

Acute hemodynamic effect of inhaled iloprost in pulmonary artery hypertension evaluated with echocardiography

Cardiovascular Ultrasound, 2007
Doppler echocardiography is useful in the initial evaluation and long-term follow-up of patients with pulmonary artery hypertension. Aerosolised iloprost has been shown to reduce pulmonary pressure immediately after inhalation.
Miranda Rita, Simões Otília, Cotrim Carlos, Loureiro Maria, Cordeiro Pedro, Carrageta Manuel   +5 more
doaj   +1 more source

Intratracheal administration of polystyrene microplastics induces pulmonary fibrosis by activating oxidative stress and Wnt/β-catenin signaling pathway in mice

Ecotoxicology and Environmental Safety, 2022
Polystyrene microplastics (PS-MPs) are emerging pollutants that are absorbed by organisms. Due to their small volume and strong biological permeability, they affect the biological functions of cells.
Xuran Li, Tongtong Zhang, Wenting Lv, Hui Wang, Haoran Chen, Qinghua Xu, Hourong Cai, Jinghong Dai   +7 more
doaj   +1 more source

Inhaled Iloprost for Severe Pulmonary Hypertension

New England Journal of Medicine, 2002
Uncontrolled studies suggested that aerosolized iloprost, a stable analogue of prostacyclin, causes selective pulmonary vasodilatation and improves hemodynamics and exercise capacity in patients with pulmonary hypertension.We compared repeated daily inhalations of 2.5 or 5.0 microg of iloprost (six or nine times per day; median inhaled dose, 30 microg ...
Olschewski, Horst, Simonneau, Gerald, Galie, Nazzareno, Higenbottam, Timothy, Naeije, Robert, Rubin, Lewis, Nikkho, Sylvia, Speich, Rudolf, Hoeper, Marius M., Behr, Jürgen, Winkler, Jörg, Sitbon, Olivier, Popov, Vladimir, Ardeschir Ghofrani, H., Manes, Alessandra, Kiely, David G., Ewert, Ralph, Meyer, Andreas, Corris, Paul A., Delcroix, Marion, Gomez Sanchez, Miguel Angel, Siedentop, Harald, Seeger, Werner   +22 more
openaire   +3 more sources

Inhalable PEGylated Phospholipid Nanocarriers and PEGylated Therapeutics for Respiratory Delivery as Aerosolized Colloidal Dispersions and Dry Powder Inhalers

Pharmaceutics, 2014
Nanomedicine is making groundbreaking achievements in drug delivery. The versatility of nanoparticles has given rise to its use in respiratory delivery that includes inhalation aerosol delivery by the nasal route and the pulmonary route.
Priya Muralidharan, Evan Mallory, Monica Malapit, Don Hayes, Heidi M. Mansour   +4 more
doaj   +1 more source

Irritant Inhalation Evokes P Wave Morphological Changes in Spontaneously Hypertensive Rats via Reflex Modulation of the Autonomic Nervous System

Frontiers in Physiology, 2021
Irritant inhalation is associated with increased incidence of atrial fibrillation (AF) and stroke. Irritant inhalation acutely regulates cardiac function via autonomic reflexes.
J. Shane Hooper, Thomas E. Taylor-Clark
doaj   +1 more source

Laryngitis after inhalation of liposomal amikacin

Clinical Case Reports, 2022
A 56‐year‐old woman with pulmonary Mycobacterium avium complex disease was started on inhalation liposomal amikacin. One month later, she developed hoarseness and was diagnosed with laryngitis.
Atsuho Morita, Ho Namkoong, Makoto Hosoya, Naoki Hasegawa   +3 more
doaj   +1 more source