Results 71 to 80 of about 104,967 (312)

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Novel inhalation therapy in pulmonary fibrosis: principles, applications and prospects

Journal of Nanobiotechnology
Pulmonary fibrosis (PF) threatens millions of people worldwide with its irreversible progression. Although the underlying pathogenesis of PF is not fully understood, there is evidence to suggest that the disease can be blocked at various stages ...
Meiling Zheng, Wei Zhu, Fei Gao, Yu Zhuo, Mo Zheng, Guanghao Wu, Cuiling Feng   +6 more
doaj   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon

Particle and Fibre Toxicology, 2017
Background Air pollution is a recognized aggravating factor for pulmonary diseases and has notably deleterious effects on asthma, bronchitis and pneumonia.
Cécile Vignal, Muriel Pichavant, Laurent Y. Alleman, Madjid Djouina, Florian Dingreville, Esperanza Perdrix, Christophe Waxin, Adil Ouali Alami, Corinne Gower-Rousseau, Pierre Desreumaux, Mathilde Body-Malapel   +10 more
doaj   +1 more source

Redefining the Health Risk of Battery Materials Through a Biologically Transformed Metal Mixture

Advanced Science, EarlyView.
Inhaled NCM particles undergo lysosomal degradation, releasing complex ion mixtures that induce systemic impact. The impact is determined by a critical balance between antagonistic Ni‐Co interactions and synergistic Mn effects. To capture these complexities in risk assessment, we develop an IAI model, ensuring a more accurate quantitative risk ...
Ze Zhang, Gan Miao, Xueyu Zhang, Zhao Shu, Dawei Lu, Yujie Song, Shanfa Yu, Qian Liu, Yang Song, Rong Zhang, Xiaoting Jin, Yuxin Zheng   +11 more
wiley   +1 more source

Pediatric inhalation injury

Burns & Trauma, 2017
Smoke inhalation injury can cause severe physiologic perturbations. In pediatric patients, these perturbations cause profound changes in cardiac and pulmonary physiology.
Soman Sen
doaj   +1 more source

Twenty‐Year Longitudinal Cohort Study of Cancer Incidence and Mortality Among Workers in Two Primary Aluminum Prebake Smelters

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Classified as carcinogenic to humans by the International Agency for Research on Cancer, aluminum production has been transitioning towards lower polycyclic aromatic hydrocarbon‐emitting prebake smelters. This study explored the risk of cancer and mortality over 20 years follow‐up among a cohort of aluminum prebake smelter workers ...
Natasha Kinsman, Christina Dimitriadis, Anthony Del Monaco, Geza Benke, Sophia Xie, Malcolm Sim, StellaMay Gwini, Karen Walker‐Bone   +7 more
wiley   +1 more source

Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman, Spencer Short, Emma Tam, Benjamin F. Bitner, Abdulghafoor Alani, Marc Rosen, Mindy Rabinowitz, Damaris Pena Evertz, Elina Toskala, Gurston G. Nyquist   +9 more
wiley   +1 more source

Advanced Microparticulate/Nanoparticulate Respirable Dry Powders of a Selective RhoA/Rho Kinase (Rock) Inhibitor for Targeted Pulmonary Inhalation Aerosol Delivery. [PDF]

Pharmaceutics, 2021
Muralidharan P, Hayes D, Fineman JR, Black SM, Mansour HM.   +4 more
europepmc   +1 more source

Inhaled budesonide and pulmonary sarcoidosis revisited.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
Results of a few controlled clinical studies have been reported with inhaled corticosteroids (ICS) in patients with pulmonary sarcoidosis. Some evidence of efficacy has been observed, but mainly with the ICS budesonide (BUD). These clinically important and statistically significant results are restricted to maintenance therapy with BUD after induction ...
Selroos, Olof, Brattsand, Ralph
openaire   +2 more sources