Results 101 to 110 of about 717,546 (265)

Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis

Advanced Science, EarlyView.
Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang, Hai‐jun Liu, Yan Yue, Jun‐jie Gao, Jin Zhang, Wen‐wu Zhang, Yun‐long Zhang, Wei‐hua Lu, Sheng‐wei Jin, Pu‐hong Zhang   +9 more
wiley   +1 more source

Growth Evaluation of Pulmonary Nodules on Chest CT

, 2017
Computed tomography (CT) follow-up of indeterminate pulmonary nodules and the quantification of growth characteristics are the commonly adopted strategy in clinical setting.
Datong SU, Ying WANG
core   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Clinical application of serum seven tumour-associated autoantibodies in patients with pulmonary nodules

Heliyon
Background: The incidence of pulmonary nodules is increasing because of the promotion and popularisation of low-dose computed tomography (LDCT) screening for populations with suspected lung cancer.
Kaiming Hu, Lili Gao, Ruyi Zhang, Meiyi Lu, Dangui Zhou, Siqi Xie, Xinyue Fan, Mei Zhu   +7 more
doaj   +1 more source

Computed Tomographic Analysis of Pulmonary Nodules [PDF]

, 1991
CT was carrid out in 33 nodules showing non-calcified nodular shadow on the chest radiographs or conventional tomograms, and measurement of CT number and preparation of the distribution chart were performed.
Nakanishi, Takashi, Higashi, Yuichiro
core  

Results of logistic regression analysis for predictors of pulmonary metastases and non-metastatic lesions in pulmonary nodules.

, 2019
Results of logistic regression analysis for predictors of pulmonary metastases and non-metastatic lesions in pulmonary nodules.
SeungHyun Lee (6316691), Woo Sun Kim (3163572), Ji Young Ha (6316688), Sang Joon Park (636317), Hee Young Shin (306133), Hyoung Jin Kang (306121), Jung-Eun Cheon (4725975), In-One Kim (5108906), Yeon Jin Cho (6316685), Young Hun Choi (3163569)   +9 more
core   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

Pulmonary nodules detected by thoracic computed tomography scan after exposure to asbestos: diagnostic significance.: Asbestos exposure and CT pulmonary nodules

, 2011
International audienceOBJECTIVE: To analyse the relationship between pulmonary nodules detected by radiologists using computed tomography and cumulative exposure to asbestos or asbestos-related pleuro-pulmonary diseases in 5662 asbestos-exposed subjects,
E. Schorle, Schorle, Evelyne, A. Luc, Ameille, Jacques, F. Laurent, Gislard, Antoine, de Girolamo, Julien, Launoy, Guy, J. Ameille, B. Clin, A. Gislard, J. De Girolamo, G. Launoy, Luc, Amandine, P. Brochard, C. Paris, Brochard, Patrick, Laurent, François, Letourneux, Marc, Paris, Chrisophe, Clin, Bénédicte, Pairon, Jean-Claude, Morlais, Fabrice, J-C. Pairon, F. Morlais, M. Letourneux   +25 more
core   +1 more source

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

Advanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai, Jingyi Tang, Huan Rong, Yu Wang, Xiangyi Zhou, Can Xu, Jianhua Wang, Lili Li, Yue Wu, Fei Deng, Dan Yang, Xiao Yang, Renyan Li, Yongzhong Wu, Dongxi Xiang, Tingxiu Xiang   +15 more
wiley   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source