Results 131 to 140 of about 41,783 (315)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.

, 2008
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains controversial. To address the impact of TLR-mediated pathogen recognition and MyD88-dependent signaling events on anti ...
Abel, Bafica, Blander, Branger, Brightbill, Carroll, Cooper, Drennan, Feng, Flynn, Flynn, Fremond, Fremond, Gilleron, Gutierrez, Han, Holscher, Holscher, Hsieh, Jones, Kamath, Kaufmann, Kaufmann, Kawai, Krieg, MacMicking, MacMicking, Maher, Martinon, Means, Means, Means, Medzhitov, North, Quesniaux, Rausch, Reiling, Ryffel, Scanga, Scanga, Schaible, Seki, Shi, Shi, Shim, Sugawara, Sugawara, Sun, Takeuchi, Thoma-Uszynski, Trinchieri, Underhill, van der Wel, Yates   +53 more
core   +1 more source

A novel alveolar Krebs cycle-triggered CO2 sensing mechanism regulates regional pulmonary ventilation. [PDF]

, 2011
Pulmonary perfusion disorders provoke atelectasis in order to minimize ventilation/perfusion mismatch. However, the underlying mechanisms remain unknown.
Alwin Goetz, Kai Heckel, Leoni Schulte-Uentrop, Martina Kiefmann, Oliver Tritt, Paula Keller, Rainer Kiefmann, Sascha Tank   +7 more
core   +1 more source

Extra-lobar Pulmonary Sequestration with Associated Asymptomatic Congenital Diaphragmatic Hernia [PDF]

, 2019
Shannon Longshore
openalex   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Cardiovascular, respiratory and splenic responses to rebreathing and apnoea during exercise

Experimental Physiology, EarlyView.
Abstract We investigated integrative physiological responses to eupnoeic exercise (EX), rebreathing exercise (RB), dynamic apnoea (DA) and dynamic apnoea with cold‐water face immersion (DAFI) in 20 healthy participants. Trials involved non‐steady‐state cycle exercise at 60 W for an average duration of 66 s.
Theodore Dotevall, Maja Persson, Bodil Sjögreen, Mats H. Linér, Angelica Lodin‐Sundström, Johan P. A. Andersson   +5 more
wiley   +1 more source

Pulmonary Sequestration

Scandinavian Journal of Thoracic and Cardiovascular Surgery, 1973
I, Enge, O, Friestad
  +9 more sources

Interaction of mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy [PDF]

, 2018
Tuberculosis (TB) is an ancient disease remaining a serious health threat worldwide. It is caused by Mycobacterium tuberculosis (Mtb), an acid-fast bacilli, non-sporulated, slow-growing, immobile and aerobic.
Colombo, Maria Isabel, Giai, Constanza, Zarelli, Valeria Eugenia Paola   +2 more
core  

Economic Burden of Sickle Cell Disease: A Retrospective Study of Pediatric and Adult Individuals With Medicaid Coverage From 2016 to 2020

American Journal of Hematology, Volume 101, Issue 2, Page 269-280, February 2026.
ABSTRACT There is limited information regarding the contemporary real‐world clinical and financial burden of Medicaid enrollees with sickle cell disease (SCD) in the United States. Using the IBM MarketScan Medicaid database (7/2016–12/2020), individuals with ≥ 3 SCD diagnoses were matched 1:1 on age, gender, and race to individuals without SCD ...
Giovanna Tedesco Barcelos, Telma Peixoto, Jose Alvir, Jay Lin, Christine L. Baker   +4 more
wiley   +1 more source

LABRAD : Vol 32, Issue 2 - May 2007 [PDF]

, 2007
Transcription Mediated Amplification for the Diagnosis of HCV RNA Vanillyl Mandelic Acid Diagnosis of Pneumocystic Jiroveci Infection in Microbiology Laboratory Lab Diagnosis of Metabolic Bone Diseases 24 Hours Urinary Specimen Collection Genetic ...
Aga Khan University Hospital, Karachi
core   +1 more source