Results 171 to 180 of about 74,178 (294)

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

open access: yesCell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao   +6 more
wiley   +1 more source

MR Imaging of Pulmonary Surfactant Distribution in a Preclinical Neonatal Lung Model. [PDF]

open access: yesNMR Biomed
Marfouk O   +11 more
europepmc   +1 more source

Update on innovative surgical techniques for omphalectomy in foals

open access: yesEquine Veterinary Education, EarlyView.
Summary Umbilical infection is a common foal disorder, prone to complications, requiring surgical excision in severe cases. Timely surgical excision is the treatment of choice in these cases, as the infected umbilicus places the foal at risk for further fatal complications, such as sepsis and septic arthritis.
O. Haion   +3 more
wiley   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

open access: yesThe FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu   +9 more
wiley   +1 more source

An update on the landscape of collagen bioactive fragments

open access: yesThe FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Home - About - Disclaimer - Privacy