Results 191 to 200 of about 685,376 (295)

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

Cell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li, Dingyun Song, Faguo Sun, Licheng Song, Bin An, Tingting Gao, Jingjing Liu, Kan Zhang, Kaidi Liu, Kaiwei Wu, Yajing Li, Yi Yang, Yaru Liu, Ruofan Su, Zai Wang, Tiemei Zhao, Huaiyong Chen, Li Xiao, Liang Peng, Liu Wang, Wei Li, Lixin Xie, Jie Hao, Huaping Dai, Jun Wu   +24 more
wiley   +1 more source

Pulmonary surfactant-biomimetic membranized coacervate injection for acute respiratory distress syndrome therapy. [PDF]

Acta Pharm Sin B
Chen W, Xie Q, Zhou Z, Kang J, Gao Y, Zhang H, Batur S, Fu C, Li Y, Yang C, Kong L, Zhang Z.   +11 more
europepmc   +1 more source

Progressive Pulmonary Alveolar Proteinosis Diagnosis Masking Pneumonic Lung Carcinoma: Anchoring Bias in Critical Care

Cytopathology, EarlyView.
A presumed case of pulmonary alveolar proteinosis with clinical deterioration was ultimately identified at autopsy as pneumonic‐type pleomorphic carcinoma. This case highlights the diagnostic overlap between diffuse lung diseases and the risk of anchoring bias in critically ill patients.
Dakota Wheeler, Rhaya Murray, Teklu Legesse, Hector Mesa   +3 more
wiley   +1 more source

Prospective, Non-Blinded, Randomized Controlled Trial of Pulmonary Surfactant Administration Guided by Lung Ultrasound in Preterm Infants with Gestational Age < 32 Weeks. [PDF]

Children (Basel)
Zhang J, Yuan J, Xu J, Han T, Zhang Y, Liu H, Lu D, Liu Y.   +7 more
europepmc   +1 more source

[Retracted] Mechanism of IL‑8‑induced acute lung injury through pulmonary surfactant proteins A and B. [PDF]

Exp Ther Med
Yang Y, Li Q, Tan F, Zhang J, Zhu W.
europepmc   +1 more source

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Lung ultrasound imaging can effectively monitor and guide treatment with pulmonary surfactant for preterm infants of pulmonary consolidation: a prospective observational cohort study. [PDF]

Front Pediatr
Zaili F, Na H.
europepmc   +1 more source

Vasopressin Use in Extremely Preterm Infants With Refractory Cardiopulmonary Instability: Physiological Response and Mortality‐Associated Factors

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective To evaluate the physiological response following vasopressin initiation and identify factors associated with mortality in extremely preterm infants with refractory cardiopulmonary instability. Study Design Retrospective cohort study of infants born at less than 29 weeks' gestation who received vasopressin. Physiological responses and
Faisal Alamer, Kamal Ali, Saif Alsaif, Mohanned Alrahili, Mohammed Almahdi, Eman Bazbouz, Rana Almuqati, Saad Alshareedah, Faisal Alsehli, Abdulaziz Homedi   +9 more
wiley   +1 more source

The biophysical function of pulmonary surfactant. [PDF]

Biophys J
Hall SB, Zuo YY.
europepmc   +1 more source

Lung Ultrasound Practice in Australian and New Zealand Neonatal Intensive Care Units—A Survey

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Introduction Lung ultrasound (LUS) is increasingly used in neonatal intensive care units (NICUs) as a bedside, radiation‐free imaging tool for assessing respiratory conditions. Despite its advantages, data on current LUS practices in Australasian NICUs are limited. This study aimed to evaluate LUS use across NICUs in both countries.
V. Gruber, S. Morakeas, B. Schwaberger, M. B. Tracy   +3 more
wiley   +1 more source