Results 281 to 290 of about 1,404,214 (346)

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Coarse-Grained Molecular Dynamics Study on Polyethylenimine-Based Nanoparticles for Pulmonary Gene Delivery: From Model Development to Surfactant Crossing Simulation

Hashemi, Seyedehniloofar
openalex   +1 more source

Effect of Pulmonary Surfactant on Antimicrobial Activity In Vitro

Antimicrobial Agents and Chemotherapy, 2013
R. Schwameis, Z. Erdogan-Yildirim, Mohammad Manafi, M. Zeitlinger, Sabine Strommer, R. Sauermann   +5 more
semanticscholar   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Pulmonary surfactant impacts in vitro activity of selected antifungal drugs against Candida krusei and Candida albicans. [PDF]

Eur J Clin Microbiol Infect Dis
Nussbaumer-Pröll A, Matzneller P, Eberl S, Zeitlinger M.   +3 more
europepmc   +1 more source

Preparation and Characterization of Pulmonary Surfactant-Super Oxide Dismutase Liposomes

, 2009
Shazia Bashir, Abdul Manan, Mubashir Beigh, Abdul Hanan, Rajeev Sharma, Sheikh Irfan, Muhammad Amjad Bashir, M Resident, Rashid Mubashir   +8 more
openalex   +2 more sources

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Caregivers' Experiences With Involuntary Oral Care for Individuals With Dementia Within the Dutch Care and Coercion Act

Gerodontology, EarlyView.
ABSTRACT Background Individuals with dementia frequently show care‐resistant behaviour toward the provision of oral care. Providing oral care despite care‐resistant behaviour is legally considered to be involuntary oral care. In the Netherlands, the provision of involuntary oral care to incapacitated individuals with dementia is regulated by the Care ...
Maud Jonker, Coos Engelsma, David J. Manton, Anita Visser   +3 more
wiley   +1 more source

Dipalmitoylphosphatidylcholine and cholesterol in monolayers spread from adsorbed films of pulmonary surfactant

, 2001
Shou-Hwa Yu, Fred Possmayer
openalex   +1 more source

Effects of Dental Treatments on the Recovery of Oral Function Associated With Dietary Intake in Subacute Stroke Patients: A Multi‐Center Prospective Study

Journal of Oral Rehabilitation, EarlyView.
This study examined the effects of dental treatments on the recovery of oral function in patients with subacute stroke in convalescent rehabilitation. The findings highlight the importance of dental treatments during stroke recovery. ABSTRACT Background Compromised oral function in patients with stroke hinders the recovery of oral food intake and ...
Koichiro Matsuo, Tomohisa Ohno, Masako Kishima, Yasuyuki Iwasa, Satoshi Teranaka, Daisuke Kanamori, Rena Hidaka, Junichi Furuya   +7 more
wiley   +1 more source