Results 121 to 130 of about 338,921 (264)

ERS Congress 2025: highlights from the Pulmonary Vascular Diseases Assembly. [PDF]

ERJ Open Res
Budhram B, Genecand L, Zeder K, Baccelli A, Bokan A, Cullivan S, Park DH, Foris V, Grynblat J, Jutant EM, Maloir Q, Raza A, Riou M, Robert F, Tenes A, Valentin S, Bogaard HJ, Sitbon O, Boucly A.   +18 more
europepmc   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

Effect of sildenafil on resting and exercise haemodynamics in hypoxia in patients with pulmonary vascular diseases: data from a randomised controlled trial. [PDF]

ERJ Open Res
Lichtblau M, Schneider SR, Müller J, Bauer M, Carta AF, Mayer L, Schwarz EI, Furian M, Saxer S, Ulrich S.   +9 more
europepmc   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

ERS Congress 2024: highlights from the Pulmonary Vascular Diseases Assembly. [PDF]

ERJ Open Res
Foris V, Bokan A, Zeder K, Cuomo A, Sitbon O, Vonk Noordegraaf A, Lichtblau M, Boucly A.   +7 more
europepmc   +1 more source

Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli

Advanced Science, EarlyView.
Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma, Yuxin Zhang, Lujia Sun, Hong Jiang, Fan Li, Wenming Liu, Shenao Zhou, Mengting Wang, Weijian Huang, Xu Zhou, Caiyang Chen, Qiuqiu Zhang, Xiaoyan Jin, Feihan Yan, Hongping Wu, Yonghong Yin, Xinling Wang, Hexin Yan, Weifeng Yu   +18 more
wiley   +1 more source

Alterations in Mitochondrial Function in Pulmonary Vascular Diseases. [PDF]

Antioxid Redox Signal
Farha S, Asosingh K, Hassoun PM, Barnard J, Comhair S, Reichard A, Wanner N, Radeva M, Aldred MA, Beck GJ, Berman-Rosenzweig E, Borlaug BA, Finet JE, Frantz RP, Grunig G, Hemnes AR, Hill N, Horn EM, Jellis C, Leopold JA, Mehra R, Park MM, Rischard FP, Tang WHW, Erzurum SC, PVDOMICS Study Group.   +25 more
europepmc   +1 more source

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Editorial: Immunity and pulmonary vascular diseases: challenges, advances and future perspectives. [PDF]

Front Immunol
Jin Q, Zhou D, Liu Z, Kosanovic D.
europepmc   +1 more source

Updates in pulmonary hypertension and other pulmonary vascular diseases. [PDF]

Breathe (Sheff), 2019
Bernardo RJ, Bokan A, Ramjug S.
europepmc   +1 more source