Results 161 to 170 of about 478,311 (305)

CRISPR‐Cas9‐Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real‐Time MRI Monitoring

Advanced Science, EarlyView.
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang   +10 more
wiley   +1 more source

Editorial: Immunity and pulmonary vascular diseases: challenges, advances and future perspectives. [PDF]

Front Immunol
Jin Q, Zhou D, Liu Z, Kosanovic D.
europepmc   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

Pulmonary vascular diseases at high altitude - is it safe to live in the mountains? [PDF]

Curr Opin Pulm Med
Titz A, Hoyos R, Ulrich S.
europepmc   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Infection and pulmonary vascular diseases consortium: United against a global health challenge. [PDF]

Pulm Circ
Oliveira SD, Almodóvar S, Butrous G, De Jesus Perez V, Fabro A, Graham BB, Mocumbi A, Nyasulu PS, Tura-Ceide O, Oliveira RKF, Dhillon NK, Infection and Pulmonary Vascular Diseases Consortium.   +11 more
europepmc   +1 more source

Updates in pulmonary hypertension and other pulmonary vascular diseases. [PDF]

Breathe (Sheff), 2019
Bernardo RJ, Bokan A, Ramjug S.
europepmc   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Causal association between epigenetic age acceleration and two pulmonary vascular diseases: pulmonary arterial hypertension and pulmonary embolism-a bidirectional Mendelian study. [PDF]

Clin Epigenetics
Tong J, Wan C, Wang A, Chen M, Ruan B, Shen J.   +5 more
europepmc   +1 more source

Infection in pulmonary vascular diseases: Would another consortium really be the way to go? [PDF]

Glob Cardiol Sci Pract, 2019
Butrous G, Mathie A.
europepmc   +1 more source