Results 221 to 230 of about 478,311 (305)

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Mechanisms Underlying Altitude-Induced and Group 3 Pulmonary Hypertension. [PDF]

Int J Mol Sci
Milano G, Ottolenghi S, Zubieta-Calleja G, Beghetti M, Samaja M.   +4 more
europepmc   +1 more source

Reactive Oxygen Species–Induced Modifications of Fibrin Clots as a Link Between Immune Responses and Atherothrombosis in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. Although oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

Integrated Stress Response (ISR) Modulators in Vascular Diseases. [PDF]

Cells
Kalinin A, Zubkova E, Beloglazova I, Parfyonova Y, Menshikov M.   +4 more
europepmc   +1 more source

A window on the lung: Molecular imaging as a tool to dissect pathophysiologic mechanisms of acute lung disease [PDF]

, 2019
Musch, Guido
core   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Glucose Metabolic Enzyme PFKFB3 in Cardiopulmonary Vascular Health and Disease. [PDF]

Circ Res
Li Y, Loscalzo J, Xiao W.
europepmc   +1 more source

Telomere Length of Peripheral Blood Leukocytes Predicts Disease Severity and Worse Survival in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Peripheral blood leukocyte telomere length (PBL‐TL) shortening is associated with systemic sclerosis–related interstitial lung disease (SSc‐ILD). However, its association with other organ involvement, disease severity, and survival remains unclear.
Monica M. Yang, Shuo Liu, Michael Wax II, Seoyeon Lee, Sarah French, Paul J. Wolters, Francesco Boin   +6 more
wiley   +1 more source

Beta-3 Adrenoreceptor Agonist Mirabegron Improves Right Ventricular Function in a Rat Monocrotaline-Induced Pulmonary Hypertension Model. [PDF]

Pulm Circ
Mendes-Ferreira P, Tielemans B, Wagenaar A, Bouzin C, Adão R, Pokreisz P, De Mulder D, Leite-Moreira A, Brás-Silva C, Balligand JL, Dessy C, Delcroix M, Quarck R, Belge C.   +13 more
europepmc   +1 more source

S1PR2 Signaling in the Lung: Understanding Its Role in Health and Disease. [PDF]

Cells
Ha AW, Garcia JGN, Dudek SM.
europepmc   +1 more source