Results 161 to 170 of about 159,526 (403)

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Catheter pulmonary vein isolation with drug testing of dormant conduction and detection of non-pulmonary vein triggers and high frequency stimulation of left atrial ganglionated plexi in patients with paroxysmal atrial fibrillation

Патология кровообращения и кардиохирургия, 2018
Background. Catheter pulmonary vein isolation (PVI) is the main interventional procedure for treatment of atrial fibrillation (AF). Recurrences of arrhythmia paroxysms in the postoperative period are mainly determined by reconnection of conduction from ...
Yu. S. Krivosheev , D. I. Bashta, A. A. Simonyan, N. A. Tihonova, K. V. Modnikov, T. A. Myznikova, Z. A. Mishodzheva, V. N. Kolesnikov   +7 more
doaj   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Long-standing Persistent Atrial Fibrillation Ablation in a Patient With High Risk of Bleeding

Journal of Cardiac Arrhythmias, 2020
A 57 year-old patient with dilated cardiomyopathy, long-standing persistent atrial fibrillation, heart failure and episodes of gastrointestinal bleeding underwent AF ablation with pulmonary vein isolation, homogeneization of septal scar, posterior wall ...
Cristiano Pisani, Muhieddine Chokr, Carina Hardy, Sissy Lara, Mauricio Scanavacca   +4 more
doaj   +4 more sources

Predictors of Phrenic Nerve Injury During Pulmonary Vein Isolation for Curing Atrial Fibrillation With Balloon-Based Visually Guided Laser Ablation

, 2021
Shinichi Tachibana, Kaoru Okishige, Koji Sudo, Takatoshi Shigeta, Yuichiro Sagawa, Rena Nakamura, Manabu Kurabayashi, Yasuteru Yamauchi, Masahiko Goya, Tetsuo Sasano   +9 more
openalex   +2 more sources

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Pulmonary vein isolation after left-sided pneumonectomy: technically challenging but feasible and instructive [PDF]

, 2009
Melanie Konstantinidou, Boris Schmidt, Feifan Ouyang, Buelent Koektuerk, Karl Heinz Kuck, Kyoung-Ryul Julian Chun   +5 more
openalex   +1 more source

Ambulatory pulmonary vein isolation workflow using suture-mediated vascular closure devices: a prospective observational cohort study [PDF]

, 2022
Davide Fabbricatore, Niya Mileva, Chiara Valeriano, Dimitri Buytaert, P Paolisso, P Paolisso, P Geelen, P Geelen, Tom De Potter   +8 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

PO-01-187 FEASIBILITY OF FLUOROLESS PULMONARY VEIN ISOLATION USING A SINGLE-SHOT CONFORMABLE PULSED FIELD ABLATION CATHETER [PDF]

, 2023
Emmanuel Ekanem, Mohit K. Turagam, Jan Petrů, Moritoshi Funasako, Jacob S. Koruth, Petr Neužil, Vivek Y. Reddy   +6 more
openalex   +1 more source