Results 161 to 170 of about 180,777 (427)

Advanced ablation strategies for management of post-surgical atrial arrhythmias. [PDF]

, 2013
Post-surgical arrhythmias include a wide range of arrhythmias occurring late after cardiac surgery and represent a complex substrate for catheter ablation either because of extended scar and remodeling or because of limited access to the area of interest.
Babu-Narayan, SV, Ernst, S, Mantziari, L, Suman-Horduna, I   +3 more
core   +1 more source

Lactylation‐Driven HECTD2 Limits the Response of Hepatocellular Carcinoma to Lenvatinib

Advanced Science, Volume 12, Issue 15, April 17, 2025.
HECTD2 serves as an E3 ubiquitin ligase of KEAP1 to facilitate the antioxidative response and contributes to lenvatinib resistance in hepatocellular carcinoma. Lactylation of histone 3 on lysine residue 18 drives HECTD2 transcription. Targeting HECTD2 using PLGA‐PEG‐based nanoparticles offers novel strategies to overcome lenvatinib resistance in ...
Runyu Dong, Yao Fei, Yiren He, Peng Gao, Bo Zhang, Menglin Zhu, Zhixiong Wang, Longfei Wu, Shuai Wu, Xiaoming Wang, Juan Cai, Zhiqiang Chen, Xueliang Zuo   +12 more
wiley   +1 more source

Geometric analysis on the unidirectionality of the pulmonary veins for atrial reentry [PDF]

arXiv, 2013
It is widely believed that the pulmonary veins (PVs) of the atrium play the central role in the generation of atrial reentry leading to atrial fibrillation, but its mechanism has not been analytically explained. In order to improve the current clinical procedures for atrial reentry by understanding its mechanism, geometrical analysis is proposed on the
arxiv  

Use of Ablation Index-Guided Ablation Results in High Rates of Durable Pulmonary Vein Isolation and Freedom From Arrhythmia in Persistent Atrial Fibrillation Patients: The PRAISE Study Results

Circulation: Arrhythmia and Electrophysiology, 2018
Background: Catheter ablation for persistent atrial fibrillation (AF) is associated with less favorable outcomes than for paroxysmal AF. Substrate modification is often added to pulmonary vein isolation (PVI) to try to improve success rates.
A. Hussein, M. Das, S. Riva, M. Morgan, Christina Ronayne, Ankita Sahni, M. Shaw, D. Todd, M. Hall, S. Modi, A. Natale, A. Dello Russo, R. Snowdon, D. Gupta   +13 more
semanticscholar   +1 more source

Transfusion‐Related Acute Lung Injury: from Mechanistic Insights to Therapeutic Strategies

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This review systematically presents an updated and comprehensive overview of transfusion‐related acute lung injury (TRALI), a serious complication of blood transfusions. It explores TRALI's clinical features, potential causes, and immune mechanisms. Key insights include the roles of signaling pathways and possible therapies, with a focus on prevention ...
Xiaobin Fang, Chunheng Mo, Ling Zheng, Fei Gao, Fu‐Shan Xue, Xiaochun Zheng   +5 more
wiley   +1 more source

Adenosine-guided pulmonary vein isolation versus conventional pulmonary vein isolation in patients undergoing atrial fibrillation ablation: An updated meta-analysis [PDF]

, 2017
BACKGROUND: Recurrent atrial fibrillation episodes following pulmonary vein isolation (PVI) are frequently due to reconnection of PVs. Adenosine can unmask dormant conduction, leading to additional ablation to improve AF-free survival.
Adragao, P, Bronis, K, Cavaco, D, Chow, A, Costa, FM, Hunter, RJ, Lambiase, PD, Lowe, M, Papageorgiou, N, Providencia, R, Rowland, E, Schilling, RJ, Segal, OR, Srinivasan, N, Tousoulis, D   +14 more
core  

Force‐sensing catheters during pediatric radiofrequency ablation: The FEDERATION Study [PDF]

, 2017
Background Based on data from studies of atrial fibrillation ablations, optimal parameters for the TactiCath (TC; St. Jude Medical, Inc) force‐sensing ablation catheter are a contact force of 20 g and a force‐time integral of 400 
Avari Silva, Jennifer N, Bowman, Tammy, Dalal, Aarti S, Nguyen, Hoang H, Van Hare, George F   +4 more
core   +2 more sources

Use of IT tools to search for a correlation between weather factors and onset of pulmonary thromboembolism [PDF]

arXiv, 2020
Pulmonary embolism (PE) and deep vein thrombosis (DVT) are gathered in venous thromboembolism (VTE) and represent the third cause of cardiovascular diseases. Recent studies suggest that meteorological parameters as atmospheric pressure, temperature, and humidity could affect PE incidence but, nowadays, the relationship between these two phenomena is ...
arxiv  

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

Automated segmentation of the pulmonary arteries in low-dose CT by vessel tracking [PDF]

arXiv, 2011
We present a fully automated method for top-down segmentation of the pulmonary arterial tree in low-dose thoracic CT images. The main basal pulmonary arteries are identified near the lung hilum by searching for candidate vessels adjacent to known airways, identified by our previously reported airway segmentation method.
arxiv