Results 141 to 150 of about 1,417,297 (301)

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Rational Design of a Synthetic Galliphore for the Diagnostic Nuclear Imaging and Treatment of Bacterial Infections

Angewandte Chemie, EarlyView.
KO‐NH2 is a synthetic metallophore that preferentially binds Ga3+ over Fe3+ and is recognized by bacterial transporters. Photocrosslinking identifies CirA and Fiu as key uptake proteins in E. coli. KO‐NH2 enables targeted imaging and treatment of E. coli soft tissue infections.
Phuong Nguyen Tran, Axia Marlin, Edith K. Amason, Marie Huynh, Hannah Carlisle, Eszter Boros   +5 more
wiley   +2 more sources

Experience with the "trefoil" method for left common pulmonary vein isolation

Кардиоваскулярная терапия и профилактика
Aim. To evaluate the clinical efficacy and safety of antral segmental balloon left common pulmonary vein (LCPV) isolation using the "trefoil" method and to identify clinical and echocardiographic factors associated with the procedure success.Material and
A. G. Saribekyan, A. A. Abdullaeva, G. Yu. Simonyan, A. A. Brutyan, T. G. Brontwein, M. S. Kharlap, E. V. Bazaeva, K. V. Davtyan   +7 more
doaj   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source

Chlorination‐Driven BODIPY Fluorescent Probes for the Selective Monitoring of Myeloperoxidase Activity in Cells and Inflamed Mouse Models

Angewandte Chemie, EarlyView.
A meso‐carboxamide‐substituted BODIPY fluorescent probe reports myeloperoxidase (MPO) activity via electrophilic chlorination by MPO‐derived HOCl, generating a highly emissive chlorinated product with a ca. 40 nm bathochromic shift. Applications in quantitative MPO assays, cellular imaging of MPO‐derived HOCl, redox‐dependent discrimination of cancer ...
Siyoung Cho, Yongyang Luo, Jeehyeon Bae, Youngmi Kim   +3 more
wiley   +2 more sources

Recurrent Pulmonary Vein Stenosis After Pulmonary Vein Isolation

Journal of Cardiothoracic and Vascular Anesthesia, 2017
Khamooshian, Arash, Hai, Ting, Amador, Yannis, Jeganathan, Jelliffe, Matyal, Robina   +4 more
openaire   +3 more sources

Importance of Terminating Pulmonary Vein Fibrillation for Complete Pulmonary Vein Isolation

Circulation Journal, 2020
Chen, Songwen, Xu, Juan, Wu, Xiaoyu, Liu, Shaowen   +3 more
openaire   +3 more sources

Phase II Study of Posttransplant Cyclophosphamide‐Based Graft‐Versus‐Host Disease Prophylaxis After HLA‐Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion Cohort

American Journal of Hematology, EarlyView.
ABSTRACT Posttransplant cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD) improves outcomes in recipients of HLA mismatched unrelated donor (MMUD) allogeneic hematopoietic cell transplantation (allo HCT). Outcomes of MMUD HCT using PTCy in patients requiring reduced intensity or non‐myeloablative conditioning (RIC/NMA) are not well ...
Brian C. Shaffer, Monzr M. Al Malki, Antonio Martin Jimenez Jimenez, Joseph Stanek, Stephanie Bo‐Subait, Brent R. Logan, Jianqun Kou, Erin Leckrone, Heather E. Stefanski, Stephen R. Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Dipenkumar Modi, Farhad Khimani, Mehdi Hamadani, Martin Maiers, Rachel Cook, Karen Ballen, Javier Bolaños‐Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William J. Hogan, Ran Reshef, Satyajit Kosuri, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Won Choi, Larisa Broglie, Jeffery J. Auletta, Bronwen E. Shaw, Steven M. Devine, Mahasweta Gooptu   +38 more
wiley   +1 more source

Pulmonary-vein isolation for atrial fibrillation in patients with heart failure

, 2008
Background Pulmonary-vein isolation is increasingly being used to treat atrial fibrillation in patients with heart failure. Methods In this prospective, multicenter clinical trial, we randomly assigned patients with symptomatic, drug-resistant atrial ...
A. BONSO, R. SCHWEIKERT, W. SALIBA, J. KAUTZNER, A. AL AHMAD, R. FANELLI, V. SCHIBGILLA, M. CASELLA, M. HAÏSSAGUERRE, A. RAVIELE, P. WANG, S. BEHEIRY, G. PELARGONIO, R. MASSARO, J. CUMMINGS, A. DELLO RUSSO, P. SANDERS, J. BRACHMANN, DI BIASE, LUIGI, S. HAO, P. SANTARELLI, P. JAÏS, O. WAZNI, D. O. MARTIN, S. THEMISTOCLAKIS, M. N. KHAN, D. POTENZA, R. C. STARLING, A. NATALE   +28 more
core  

Anatomical extent of pulmonary vein isolation after cryoballoon ablation for atrial fibrillation: comparison between the 23 and 28 mm balloons

, 2011
Item does not contain fulltextBACKGROUND: Pulmonary vein isolation seems to occur in the distal part of the ostium leaving the atrium largely unablated when using the 23 mm cryoballoon catheter ablation for atrial fibrillation.
Pedro Brugada, Chierchia, G.B., Yazaki, Y., Gaetano Paparella, Paparella, G., Capulzini, L., Carlo de Asmundis, Yoshinao Yazaki, Andrea Sarkozy, Lucio Capulzini, Sorgente, A., Brugada, P., Sarkozy, A., Asmundis, C. de, Stephan-Andreas Müller-Burri, Gian B Chierchia, Muller-Burri, S.A., Antonio Sorgente   +17 more
core   +1 more source